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Anti-AKR1A1 Antibody

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产品名称: Anti-AKR1A1 Antibody
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简单介绍

Anti-AKR1A1 Antibody


Anti-AKR1A1 Antibody  的详细介绍
Name: Anti-AKR1A1 Antibody
See all AKR1A1 primary antibodies
Description: Rabbit polyclonal antibody to AKR1A1.
Applications: WB, IHC, IF
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:10 - 1:100.
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human AKR1A1.
Protein Length: 325
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).
Tissue Specificity: Widely expressed. Highly expressed in kidney, salivary gland and liver. Detected in trachea, stomach, brain, lung, prostate, placenta, mammary gland, small intestine and lung.
Sequence Similarities: Belongs to the aldo/keto reductase family.
Database Links:
  • Entrez Gene: 10327?Human
  • Entrez Gene: 58810?Mouse
  • Entrez Gene: 78959?Rat
  • Omim: 103830?Human
  • SwissProt: P14550?Human
  • SwissProt: Q9JII6?Mouse
  • SwissProt: P51635?Rat
  • Unigene: 474584?Human
  • Unigene: 30085?Mouse
  • Unigene: 835?Rat
    		•
    Synonyms:
  • AK1A1_HUMAN Antibody
  • AKR1A1 Antibody
  • Alcohol dehydrogenase Antibody
  • Alcohol dehydrogenase [NADP+] Antibody
  • Aldehyde reductase Antibody
  • Aldo keto reductase family 1 member A1 (aldehyde reductase) Antibody
  • Aldo-keto reductase family 1 member A1 Antibody
  • ALDR1 Antibody
  • ALR Antibody
  • ARM Antibody
  • DD3 Antibody
  • MGC12529 Antibody
  • MGC1380 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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