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Anti-AFP Antibody

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产品名称: Anti-AFP Antibody
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Anti-AFP Antibody


Anti-AFP Antibody  的详细介绍
Name: Anti-AFP Antibody
See all AFP primary antibodies
Description: Rabbit polyclonal antibody to AFP
Specificity: The antibody detects endogenous level of total AFP protein.
Applications: WB, IHC, IF
Reactivity: Human, Mouse, Rat
Immunogen: A synthetic peptide of human AFP .
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antibodies were purified by affinity purification using immunogen.
Concentration: 1.0mg / ml
Formulation: Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20?C
Function: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.
Tissue Specificity: Plasma. Synthesized by the fetal liver and yolk sac.
Involvement in Disease: Alpha-fetoprotein deficiency: A benign condition characterized by undetectable AFP levels in the amniotic fluid. Affected individuals are asymptomatic and present normal development.

Alpha-fetoprotein, hereditary persistence: A benign autosomal dominant condition characterized by continued expression of alpha-fetoprotein in ***** life.
Sequence Similarities: Belongs to the ALB/AFP/VDB family.
Post-Translational Modification: Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence.
Cellular Location: Secreted.
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