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Anti-Actin Antibody

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产品名称: Anti-Actin Antibody
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简单介绍

Anti-Actin Antibody


Anti-Actin Antibody  的详细介绍
Name: Anti-Actin Antibody
See all Actin primary antibodies
Description: Mouse monoclonal (HHF35) antibody to Actin.
Specificity: The mouse monoclonal antibody HHF35 recognizes muscle-specific alpha and gamma actin (42 kDa) in various species. This antibody stains skeletal, smooth and myocardial cells as well as myoepithelial cells and pericytes of small vessels. It is a widely used marker of muscle and muscle-derived cells.
Applications: WB, IHC-P, IHC-Fr
Reactivity: Human, Non-Human Primates, Mouse, Rat, Dog, Cat, Rabbit, Chicken
Immunogen: SDS extracted protein fraction of human myocardium.
Host: Mouse
Clonality: Monoclonal
Clone: HHF35
Isotype: IgG1
Conjugate: Unconjugated
Purification: Protein A chromatography.
Concentration: 1 mg/ml
Purity: > 95% (by SDS-PAGE)
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.4, with 15mM Sodium Azide.
Storage: Store at 2-8°C.
Function: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Sequence Similarities: Belongs to the actin family.
Post-Translational Modification: Oxidation of Met-46 and Met-49 by MICALs (MICAL1, MICAL2 or MICAL3) to form methionine sulfoxide promotes actin filament depolymerization. MICAL1 and MICAL2 produce the (R)-S-oxide form. The (R)-S-oxide form is reverted by MSRB1 and MSRB2, which promotes actin repolymerization.
Cellular Location: Cytoplasm > Cytoskeleton.
Database Links:
  • Entrez Gene: 421534?Chicken
  • Entrez Gene: 58?Human
  • Entrez Gene: 11459?Mouse
  • Entrez Gene: 29437?Rat
  • Omim: 102610?Human
  • SwissProt: P68139?Chicken
  • SwissProt: P68133?Human
  • SwissProt: P68134?Mouse
  • SwissProt: P68135?Rabbit
  • SwissProt: P68136?Rat
  • Unigene: 1288?Human
  • Unigene: 214950?Mouse
  • Unigene: 82732?Rat
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    Synonyms:
  • a actin Antibody
  • ACTA Antibody
  • ACTA1 Antibody
  • Actin Antibody
  • Actin alpha skeletal muscle Antibody
  • actin, alpha 1, skeletal muscle Antibody
  • actin, alpha 1, skeletal muscle 1 Antibody
  • Actin, alpha skeletal muscle Antibody
  • actina Antibody
  • actine Antibody
  • ACTS_HUMAN Antibody
  • aktin Antibody
  • Alpha Actin 1 Antibody
  • alpha skeletal muscle Antibody
  • Alpha skeletal muscle Actin Antibody
  • alpha-actin Antibody
  • Alpha-actin-1 Antibody
  • ASMA Antibody
  • CFTD Antibody
  • CFTD1 Antibody
  • CFTDM Antibody
  • MPFD Antibody
  • NEM1 Antibody
  • NEM2 Antibody
  • NEM3 Antibody
  • nemaline myopathy type 3 Antibody
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    Information: Target information shown above is from the UniProt Consortium.
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