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Anti-Synaptophysin Antibody

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产品名称: Anti-Synaptophysin Antibody
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简单介绍

Anti-Synaptophysin Antibody


Anti-Synaptophysin Antibody  的详细介绍
Name: Anti-Synaptophysin Antibody
See all Synaptophysin primary antibodies
Description: Rabbit monoclonal (SP11) antibody to Synaptophysin.
Specificity: Synaptophysin, 38 kDa protein in neurectodermal tissue.
Applications: IHC
Reactivity: Human, Bovine, Mouse, Rat
Immunogen: Synthetic peptide corresponding to the C-terminus of human Synaptophysin.
Host: Rabbit
Clonality: Monoclonal
Clone: SP11
Isotype: IgG
Conjugate: Unconjugated
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.3, with 0.09% Sodium Azide.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).
Tissue Specificity: Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.
Sequence Similarities: Belongs to the synaptophysin/synaptobrevin family.
Post-Translational Modification: Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.
Cellular Location: Cytoplasmic vesicle > Secretory vesicle > Synaptic vesicle membrane. Cell junction > Synapse > Synaptosome.
Database Links:
  • Entrez Gene: 280937?Cow
  • Entrez Gene: 6855?Human
  • Entrez Gene: 20977?Mouse
  • Entrez Gene: 24804?Rat
  • Omim: 313475?Human
  • SwissProt: P20488?Cow
  • SwissProt: P08247?Human
  • SwissProt: Q62277?Mouse
  • SwissProt: P07825?Rat
  • Unigene: 632804?Human
  • Unigene: 223674?Mouse
  • Unigene: 11067?Rat
    		•
    Synonyms:
  • Major synaptic vesicle protein p38 Antibody
  • MRX96 Antibody
  • MRXSYP Antibody
  • Syn p38 Antibody
  • Synaptophysin Antibody
  • Syp Antibody
  • SYPH Antibody
  • SYPH_HUMAN Antibody
  • SypI Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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