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Anti-PUMA Antibody

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产品名称: Anti-PUMA Antibody
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简单介绍

Anti-PUMA Antibody


Anti-PUMA Antibody  的详细介绍
Name: Anti-PUMA Antibody
See all PUMA primary antibodies
Description: Rabbit monoclonal antibody to PUMA
Specificity: This antibody detects endogenous levels of PUMA and does not cross-react with related proteins.
Applications: WB, ICC/IF, IHC, FC
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant antibody.
Host: Rabbit
Clonality: Monoclonal
Conjugate: Unconjugated
Molecular Weight: ~ 20 kDa
Purity: Protein A affinity purified
Product Form: Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Function: Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.
Tissue Specificity: Ubiquitously expressed.
Sequence Similarities: Belongs to the Bcl-2 family.
Cellular Location: Mitochondrion.

Localized to the mitochondria in order to induce cytochrome c release.
Database Links:
  • Entrez Gene: 27113?Human
  • Entrez Gene: 170770?Mouse
  • Entrez Gene: 317673?Rat
  • Omim: 605854?Human
  • SwissProt: Q9BXH1?Human
  • SwissProt: Q99ML1?Mouse
  • SwissProt: Q80ZG6?Rat
  • Unigene: 467020?Human
  • Unigene: 7660?Mouse
  • Unigene: 25176?Rat
    		•
    Synonyms:
  • BBC 3 Antibody
  • Bbc3 Antibody
  • BBC3_HUMAN Antibody
  • BCL 2 binding component 3 Antibody
  • Bcl-2-binding component 3 Antibody
  • BCL2 binding component 3 Antibody
  • JFY 1 Antibody
  • JFY-1 Antibody
  • JFY1 Antibody
  • p53 up regulated modulator of apoptosis Antibody
  • p53 up-regulated modulator of apoptosis Antibody
  • p53 Upregulated Modulator of Apoptosis Antibody
  • PUMA Antibody
  • PUMA alpha Antibody
  • PUMA/JFY1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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