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Anti-MYO1C Antibody

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产品名称: Anti-MYO1C Antibody
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Anti-MYO1C Antibody


Anti-MYO1C Antibody  的详细介绍
Name: Anti-MYO1C Antibody
See all MYO1C primary antibodies
Description: Rabbit polyclonal antibody to MYO1C.
Applications: WB, IHC, IF
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100.
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human MYO1C.
Protein Length: 1063 (1028)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Involved in glucose transporter recycling in response to insulin by regulating movement of intracellular GLUT4-containing vesicles to the plasma membrane. Component of the hair cell's (the sensory cells of the inner ear) adaptation-motor complex. Acts as a mediator of adaptation of mechanoelectrical transduction in stereocilia of vestibular hair cells. Binds phosphoinositides and links the actin cytoskeleton to cellular membranes.
Sequence Similarities: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Post-Translational Modification: Isoform 2 contains a N-acetylmethionine at position 1.
Cellular Location: Cytoplasm. Nucleus.

Colocalizes with RNA polymerase II. Absent from nucleoli and does not colocalize with RNA polymerase I. Translocates to nuclear speckles upon exposure to inhibitors of RNA polymerase II transcription.
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