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Anti-MBP Antibody

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简单介绍

Anti-MBP Antibody


Anti-MBP Antibody  的详细介绍
Name: Anti-MBP Antibody
See all Myelin Basic Protein primary antibodies
Description: Mouse monoclonal (7G7) antibody to MBP.
Applications: WB, IF/ICC, IHC
Dilutions: WB:1:5,000 -1:10,000. IF/ICC and IHC: 1:1,000.
Reactivity: Human, Horse, Cow, Porcine, Chicken, Rat, Mouse
Immunogen: Purified myelin basic protein isolated from cow nerve.
Host: Mouse
Clonality: Monoclonal
Clone: 7G7
Isotype: IgG1
Conjugate: Unconjugated
Purification: Immunogen affinity purified.
Concentration: 1 mg/ml
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline with 50% Glycerol and 5mM Sodium Azide.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity).
Tissue Specificity: Found in both the central and the peripheral nervous system.
Sequence Similarities: Belongs to the myelin basic protein family.
Post-Translational Modification: As in other animals, several charge isomers may be produced as a result of optional post-translational modifications, such as phosphorylation of serine or threonine residues, deamidation of glutamine or asparagine residues, citrullination and methylation of arginine residues.
Cellular Location: Myelin membrane.

Cytoplasmic side of myelin.
Database Links:
  • Entrez Gene: 618684?Cow
  • Entrez Gene: 4155?Human
  • Entrez Gene: 17196?Mouse
  • Entrez Gene: 24547?Rat
  • Omim: 159430?Human
  • SwissProt: P02687?Cow
  • SwissProt: P02686?Human
  • SwissProt: P04370?Mouse
  • SwissProt: P02688?Rat
  • Unigene: 551713?Human
  • Unigene: 252063?Mouse
  • Unigene: 392350?Mouse
  • Unigene: 454459?Mouse
  • Unigene: 63285?Rat
    		•
    Synonyms:
  • GDB Antibody
  • Golli MBP Antibody
  • Golli MBP; myelin basic protein Antibody
  • Hemopoietic MBP Antibody
  • HMBPR Antibody
  • HUGO Antibody
  • MBP Antibody
  • MBP_CAVPO Antibody
  • MBP_HUMAN Antibody
  • MGC99675 Antibody
  • MLD Antibody
  • Myelin A1 protein Antibody
  • Myelin A1 Protein, basic Antibody
  • Myelin Basic Protein Antibody
  • Myelin Deficient Antibody
  • Myelin membrane encephalitogenic protein Antibody
  • OTTHUMP00000163776 Antibody
  • OTTHUMP00000174387 Antibody
  • OTTHUMP00000174388 Antibody
  • SHI Antibody
  • Shiverer Antibody
  • SP Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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