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Anti-EDF1 Antibody

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产品名称: Anti-EDF1 Antibody
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简单介绍

Anti-EDF1 Antibody


Anti-EDF1 Antibody  的详细介绍
Name: Anti-EDF1 Antibody
See all EDF1 primary antibodies
Description: Rabbit polyclonal antibody to EDF1.
Applications: WB
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200.
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human EDF1.
Protein Length: 148
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Transcriptional coactivator stimulating NR5A1 and ligand-dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone-induced cardiomyocytes hypertrophy and lipid metabolism.
Tissue Specificity: Expressed in brain, liver, lung, kidney and heart (at protein level). Ubiquitously expressed. More abundant in heart, pancreas, liver, intestine and adipose tissues.
Post-Translational Modification: Phosphorylated (by PKA and PKC).
Cellular Location: Cytoplasm. Nucleus.

Also nuclear upon binding to NR5A1 and treatment of cells with TPA or forskolin.
Database Links:
  • Entrez Gene: 8721?Human
  • Omim: 605107?Human
  • SwissProt: O60869?Human
  • Unigene: 174050?Human
    		•
    Synonyms:
  • CAP19 Antibody
  • EDF-1 Antibody
  • EDF1 Antibody
  • EDF1_HUMAN Antibody
  • Endothelial differentiation related factor 1 Antibody
  • Endothelial differentiation-related factor 1 Antibody
  • MBF1 Antibody
  • MGC9058 Antibody
  • Multiprotein bridging factor 1 Antibody
  • Multiprotein-bridging factor 1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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