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Anti-BBC3 Antibody

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产品名称: Anti-BBC3 Antibody
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Anti-BBC3 Antibody


Anti-BBC3 Antibody  的详细介绍
Name: Anti-BBC3 Antibody
See all BBC3 primary antibodies
Description: Rabbit monoclonal antibody to BBC3.
Applications: WB, IHC, IF, FC
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, ICC: 1:50 - 1:200, IF: 1:50 - 1:200, FC: 1:20 - 1:50.
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human BBC3.
Host: Rabbit
Clonality: Monoclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.
Tissue Specificity: Ubiquitously expressed.
Sequence Similarities: Belongs to the Bcl-2 family.
Cellular Location: Mitochondrion.

Localized to the mitochondria in order to induce cytochrome c release.
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