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Anti-ACVR1C Antibody

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产品名称: Anti-ACVR1C Antibody
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简单介绍

Anti-ACVR1C Antibody


Anti-ACVR1C Antibody  的详细介绍
Name: Anti-ACVR1C Antibody
See all ACVR1C primary antibodies
Description: Rabbit polyclonal antibody to ACVR1C.
Applications: WB, IHC
Dilutions: WB: 1:500 - 1:2000, IHC: 1:100 - 1:200.
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human ACVR1C.
Protein Length: 493
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
Tissue Specificity: Present in pancreas, heart, colon, small intestine, ovary and the hippocampus, medulla oblongata and putamen of the brain. Isoform 1, isoform 2, isoform 3 and isoform 4 are all expressed in the placenta throughout pregnancy.
Sequence Similarities: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Cellular Location: Membrane.
Database Links:
  • Entrez Gene: 130399?Human
  • Entrez Gene: 269275?Mouse
  • Entrez Gene: 245921?Rat
  • Omim: 608981?Human
  • SwissProt: Q8NER5?Human
  • SwissProt: Q8K348?Mouse
  • SwissProt: P70539?Rat
  • Unigene: 562901?Human
  • Unigene: 77751?Mouse
  • Unigene: 10580?Rat
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    Synonyms:
  • Activin A Receptor Type IC Antibody
  • Activin A receptor, type IC Antibody
  • Activin receptor like kinase 7 Antibody
  • Activin receptor type 1C precursor Antibody
  • Activin receptor type IC Antibody
  • Activin receptor type-1C Antibody
  • Activin receptor-like kinase 7 Antibody
  • ACTR IC Antibody
  • ACTR-IC Antibody
  • ACTRIC Antibody
  • ACV1C_HUMAN Antibody
  • Acvr1c Antibody
  • ACVRLK7 Antibody
  • ALK 7 Antibody
  • ALK-7 Antibody
  • ALK7 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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