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Anti-SPN Antibody

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产品名称: Anti-SPN Antibody
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Anti-SPN Antibody


Anti-SPN Antibody  的详细介绍
Name: Anti-SPN Antibody
See all SPN primary antibodies
Description: Rabbit polyclonal antibody to SPN.
Applications: WB, IHC
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200.
Reactivity: Human
Immunogen: Recombinant protein of human SPN.
Protein Length: 400
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity).
Tissue Specificity: Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas.
Post-Translational Modification: Glycosylated; has a high content of sialic acid and O-linked carbohydrate structures.
Cellular Location: Membrane.
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