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Anti-Rho A/B/C Antibody

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产品名称: Anti-Rho A/B/C Antibody
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简单介绍

Anti-Rho A/B/C Antibody


Anti-Rho A/B/C Antibody  的详细介绍
Name: Anti-Rho A/B/C Antibody
See all Rho A primary antibodies
Description: Rabbit monoclonal antibody to Rho A/B/C
Specificity: This antibody detects endogenous levels of Rho A/B/C and does not cross-react with related proteins.
Applications: WB, ICC/IF, IHC, FC
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant antibody.
Host: Rabbit
Clonality: Monoclonal
Conjugate: Unconjugated
Molecular Weight: ~ 24 kDa
Purity: Protein A affinity purified
Product Form: Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Function: Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells.
Sequence Similarities: Belongs to the small GTPase superfamily. Rho family.
Post-Translational Modification: (Microbial infection) Glycosylated at Tyr-34 by Photorhabdus asymbiotica toxin PAU_02230. Mono-O-GlcNAcylation by PAU_02230 inhibits downstream signaling by an impaired interaction with diverse regulator and effector proteins of Rho and leads to actin disassembly.
Cellular Location: Cell membrane. Cleavage furrow.

Translocates to the equatorial region before furrow formation in a ECT2-dependent manner.
Database Links:
  • Entrez Gene: 387?Human
  • Entrez Gene: 11848?Mouse
  • Entrez Gene: 117273?Rat
  • Omim: 165390?Human
  • SwissProt: P61586?Human
  • SwissProt: Q9QUI0?Mouse
  • SwissProt: P61589?Rat
  • Unigene: 247077?Human
  • Unigene: 757?Mouse
  • Unigene: 107401?Rat
  • Synonyms:
  • Aplysia ras related homolog 12 Antibody
  • ARH12 Antibody
  • ARHA Antibody
  • H 12 Antibody
  • H12 Antibody
  • Oncogene RHO H12 Antibody
  • Ras homolog family member A Antibody
  • Ras homolog gene family member A Antibody
  • Rho A Antibody
  • Rho cDNA clone 12 Antibody
  • RHO H12 Antibody
  • RHO12 Antibody
  • RhoA Antibody
  • RHOA_HUMAN Antibody
  • RHOH12 Antibody
  • Small GTP binding protein Rho A Antibody
  • Transforming protein Rho A Antibody
  • Transforming protein RhoA Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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