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Anti-Nestin Antibody

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产品名称: Anti-Nestin Antibody
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简单介绍

Anti-Nestin Antibody


Anti-Nestin Antibody  的详细介绍
Name: Anti-Nestin Antibody
See all Nestin primary antibodies
Description: Mouse monoclonal (4D11) antibody to Nestin.
Applications: WB, ICC/IF, IHC
Dilutions: WB: 1:5,000. IF/IHC: 1:500.
Reactivity: Human, Horse, Cow, Porcine, Chicken, Rat, Mouse
Immunogen: Amino acids 317-630 of human protein.
Host: Mouse
Clonality: Monoclonal
Clone: 4D11
Isotype: IgG1
Conjugate: Unconjugated
Purity: Ascites fluid.
Product Form: Liquid
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Required for brain and eye development (By similarity). Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.
Tissue Specificity: CNS stem cells.
Sequence Similarities: Belongs to the intermediate filament family.
Post-Translational Modification: Constitutively phosphorylated. This increases during mitosis when the cytoplasmic intermediate filament network is reorganized.
Database Links:
  • Entrez Gene: 10763?Human
  • Entrez Gene: 18008?Mouse
  • Omim: 600915?Human
  • SwissProt: P48681?Human
  • SwissProt: Q6P5H2?Mouse
  • SwissProt: P21263?Rat
  • Unigene: 527971?Human
  • Unigene: 331129?Mouse
  • Unigene: 9701?Rat
    		•
    Synonyms:
  • ESTM 46 Antibody
  • FLJ 21841 Antibody
  • FLJ21841 Antibody
  • Intermediate filament protein Antibody
  • Nbla00170 Antibody
  • nes Antibody
  • Nestin Antibody
  • NEST_HUMAN Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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