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Anti-MCL1 Antibody

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Anti-MCL1 Antibody


Anti-MCL1 Antibody  的详细介绍
Name: Anti-MCL1 Antibody
See all MCL1 primary antibodies
Description: Rabbit polyclonal antibody to MCL1.
Applications: WB, IHC
Dilutions: WB: 1:500 - 1:2000, IHC: 1:100 - 1:200.
Reactivity: Human, Mouse
Immunogen: A synthetic peptide of human MCL1.
Protein Length: 350
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
Sequence Similarities: Belongs to the Bcl-2 family.
Post-Translational Modification: Cleaved by CASP3 during apoptosis. In intact cells cleavage occurs preferentially after Asp-127, yielding a pro-apoptotic 28 kDa C-terminal fragment.
Cellular Location: Membrane. Cytoplasm. Mitochondrion. Nucleus > Nucleoplasm.

Cytoplasmic, associated with mitochondria.
Database Links:
  • Entrez Gene: 4170?Human
  • Entrez Gene: 17210?Mouse
  • Omim: 159552?Human
  • SwissProt: Q07820?Human
  • SwissProt: P97287?Mouse
  • Unigene: 632486?Human
  • Unigene: 1639?Mouse
    		•
    Synonyms:
  • Bcl 2 related protein EAT/mcl1 Antibody
  • Bcl-2-like protein 3 Antibody
  • Bcl-2-related protein EAT/mcl1 Antibody
  • BCL2 related Antibody
  • Bcl2-L-3 Antibody
  • BCL2L3 Antibody
  • EAT Antibody
  • Induced myeloid leukemia cell differentiation protein Mcl 1 Antibody
  • Induced myeloid leukemia cell differentiation protein Mcl-1 Antibody
  • MCL 1 Antibody
  • MCL1 Antibody
  • MCL1-ES Antibody
  • mcl1/EAT Antibody
  • MCL1L Antibody
  • MCL1S Antibody
  • MCL1_HUMAN Antibody
  • MGC104264 Antibody
  • MGC1839 Antibody
  • Myeloid Cell Leukemia 1 Antibody
  • Myeloid cell leukemia ES Antibody
  • Myeloid cell leukemia sequence 1 Antibody
  • Myeloid cell leukemia sequence 1 BCL2 related Antibody
  • Myeloid cell leukemia sequence 1 isoform 1 Antibody
  • OTTHUMP00000032794 Antibody
  • OTTHUMP00000032795 Antibody
  • TM Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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