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Anti-ID3 Antibody

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产品名称: Anti-ID3 Antibody
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简单介绍

Anti-ID3 Antibody


Anti-ID3 Antibody  的详细介绍
Name: Anti-ID3 Antibody
See all ID3 primary antibodies
Description: Rabbit polyclonal antibody to ID3.
Applications: WB, IHC, IF
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100.
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human ID3.
Protein Length: 119
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation. Inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer.
Tissue Specificity: Expressed abundantly in lung, kidney and adrenal gland, but not in ***** brain.
Cellular Location: Nucleus.
Database Links:
  • Entrez Gene: 3399?Human
  • Entrez Gene: 15903?Mouse
  • Omim: 600277?Human
  • SwissProt: Q02535?Human
  • SwissProt: P41133?Mouse
  • Unigene: 76884?Human
  • Unigene: 110?Mouse
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    Synonyms:
  • 1R21 Antibody
  • bHLHb25 Antibody
  • Class B basic helix-loop-helix protein 25 Antibody
  • DNA binding protein inhibitor ID 3 Antibody
  • DNA-binding protein inhibitor ID-3 Antibody
  • HEIR 1 Antibody
  • HEIR1 Antibody
  • Helix loop helix protein HEIR 1 Antibody
  • Helix loop helix protein HEIR1 Antibody
  • Helix-loop-helix protein HEIR-1 Antibody
  • HLH642 Antibody
  • ID 3 Antibody
  • ID like protein inhibitor HLH 1R21 Antibody
  • ID like protein inhibitor HLH 462 Antibody
  • ID-like protein inhibitor HLH 1R21 Antibody
  • ID3 Antibody
  • ID3_HUMAN Antibody
  • Inhibitor of DNA binding 3 Antibody
  • Inhibitor of DNA binding 3 dominant negative helix loop helix protein Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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