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Anti-Cytokeratin 19 (M259) Antibody

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产品名称: Anti-Cytokeratin 19 (M259) Antibody
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Anti-Cytokeratin 19 (M259) Antibody


Anti-Cytokeratin 19 (M259) Antibody  的详细介绍
Name: Anti-Cytokeratin 19 (M259) Antibody
See all Cytokeratin 19 primary antibodies
Description: Rabbit polyclonal antibody to Cytokeratin 19 (M259)
Specificity: Cytokeratin 19 (M259) pAb detects endogenous levels of Cytokeratin 19 protein.
Applications: WB, IHC, IF
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 221-270 of Human Cytokeratin 19.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 44 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Function: Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
Tissue Specificity: Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.
Sequence Similarities: Belongs to the intermediate filament family.
Database Links:
  • Entrez Gene: 3880?Human
  • Entrez Gene: 16669?Mouse
  • Entrez Gene: 360626?Rat
  • Omim: 148020?Human
  • SwissProt: P08727?Human
  • SwissProt: P19001?Mouse
  • SwissProt: Q63279?Rat
  • Unigene: 654568?Human
  • Unigene: 439699?Mouse
  • Unigene: 9359?Rat
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    Synonyms:
  • 40 kDa keratin intermediate filament Antibody
  • CK 19 Antibody
  • CK-19 Antibody
  • CK19 Antibody
  • Cytokeratin 19 Antibody
  • Cytokeratin-19 Antibody
  • K19 Antibody
  • K1C19_HUMAN Antibody
  • K1CS Antibody
  • Keratin 19 Antibody
  • Keratin type I 40 kD Antibody
  • Keratin type I 40kD Antibody
  • Keratin type I cytoskeletal 19 Antibody
  • Keratin, type I cytoskeletal 19 Antibody
  • Keratin, type I, 40 kd Antibody
  • Keratin-19 Antibody
  • KRT19 Antibody
  • MGC15366 Antibody
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    Information: Target information shown above is from the UniProt Consortium.
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