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Anti-Bmi1 Antibody

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Anti-Bmi1 Antibody


Anti-Bmi1 Antibody  的详细介绍
Name: Anti-Bmi1 Antibody
See all Bmi1 primary antibodies
Description: Mouse monoclonal antibody to Bmi1
Specificity: This antibody detects endogenous levels of Bmi1 and does not cross-react with related proteins.
Applications: WB, ICC, IHC, FC
Reactivity: Human, Mouse, Rat
Immunogen: This antibody is produced by immunizing mice with a recombinant protein corresponding to a region of Bmi1.
Host: Mouse
Clonality: Monoclonal
Conjugate: Unconjugated
Molecular Weight: ~ 37 kDa
Purity: Protein A affinity purified
Product Form: Mouse IgG2a. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Post-Translational Modification: Monoubiquitinated (By similarity). May be polyubiquitinated; which does not lead to proteasomal degradation.
Cellular Location: Nucleus. Cytoplasm.
Database Links:
  • Entrez Gene: 100532731?Human
  • Entrez Gene: 648?Human
  • Entrez Gene: 12151?Mouse
  • Entrez Gene: 307151?Rat
  • Omim: 164831?Human
  • SwissProt: P35226?Human
  • SwissProt: P25916?Mouse
  • Unigene: 380403?Human
  • Unigene: 289584?Mouse
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    Synonyms:
  • B lymphoma Mo MLV insertion region (mouse) Antibody
  • B lymphoma Mo MLV insertion region 1 homolog Antibody
  • Bmi 1 Antibody
  • Bmi1 Antibody
  • BMI1 polycomb ring finger oncogene Antibody
  • BMI1_HUMAN Antibody
  • Flvi 2/bmi 1 Antibody
  • FLVI2/BMI1 Antibody
  • MGC12685 Antibody
  • Murine leukemia viral (bmi 1) oncogene homolog Antibody
  • Oncogene BMI 1 Antibody
  • PCGF 4 Antibody
  • PCGF4 Antibody
  • Polycomb complex protein BMI 1 Antibody
  • Polycomb complex protein BMI-1 Antibody
  • Polycomb group protein Bmi1 Antibody
  • Polycomb group ring finger 4 Antibody
  • Polycomb group RING finger protein 4 Antibody
  • RING finger protein 51 Antibody
  • RNF 51 Antibody
  • RNF51 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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