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Anti-ASH2L Antibody

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产品名称: Anti-ASH2L Antibody
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Anti-ASH2L Antibody


Anti-ASH2L Antibody  的详细介绍
Name: Anti-ASH2L Antibody
See all ASH2L primary antibodies
Description: Rabbit monoclonal antibody to ASH2L
Specificity: This antibody detects endogenous levels of ASH2L and does not cross-react with related proteins.
Applications: WB, ICC/IF, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant antibody.
Host: Rabbit
Clonality: Monoclonal
Conjugate: Unconjugated
Molecular Weight: ~ 69 kDa
Purity: Protein A affinity purified
Product Form: Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Function: Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.
Tissue Specificity: Ubiquitously expressed. Predominantly expressed in ***** heart and testis and fetal lung and liver, with barely detectable expression in ***** lung, liver, kidney, prostate, and peripheral leukocytes.
Post-Translational Modification: Both monomethylated and dimethylated on arginine residues in the C-terminus. Arg-296 is the major site. Methylation is not required for nuclear localization, nor for MLL complex integrity or maintenance of global histone H3K4me3 levels.
Cellular Location: Nucleus.
Database Links:
  • Entrez Gene: 9070?Human
  • Entrez Gene: 23808?Mouse
  • Entrez Gene: 290829?Rat
  • Omim: 604782?Human
  • SwissProt: Q9UBL3?Human
  • SwissProt: Q91X20?Mouse
  • Unigene: 521530?Human
  • Unigene: 27706?Mouse
  • Unigene: 219095?Rat
  • Synonyms:
  • ASH 2 Antibody
  • ASH2 Antibody
  • Ash2 (absent small or homeotic) like Antibody
  • Ash2 (absent, small, or homeotic) like (Drosophila) Antibody
  • ASH2 LIKE Antibody
  • ASH2 like protein Antibody
  • ASH2-like protein Antibody
  • ASH2L Antibody
  • ASH2L1 Antibody
  • ASH2L2 Antibody
  • ASH2L_HUMAN Antibody
  • Bre 2 Antibody
  • Bre2 Antibody
  • Discs 2-like Antibody
  • Drosophila absent, small, or homeotic Antibody
  • Drosophila ASH2-like Antibody
  • Set1/Ash2 histone methyltransferase complex subunit ASH2 Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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