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Anti-Actin (E361) Antibody

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产品名称: Anti-Actin (E361) Antibody
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Anti-Actin (E361) Antibody


Anti-Actin (E361) Antibody  的详细介绍
Name: Anti-Actin (E361) Antibody
See all Actin primary antibodies
Description: Rabbit polyclonal antibody to Actin (E361)
Specificity: Actin (E361) pAb detects endogenous levels of Actin protein.
Applications: WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids C-terminus of Human Actin.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 45 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Function: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Involvement in Disease: Dystonia, juvenile-onset: A form of dystonia with juvenile onset. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. Patients with juvenile-onset dystonia manifest progressive, generalized, dopa-unresponsive dystonia, developmental malformations and sensory hearing loss.

Baraitser-Winter syndrome 1: A rare developmental disorder characterized by the combination of congenital ptosis, high-arched eyebrows, hypertelorism, ocular colobomata, and a brain malformation consisting of anterior-predominant lissencephaly. Other typical features include postnatal short stature and microcephaly, intellectual disability, seizures, and hearing loss.
Sequence Similarities: Belongs to the actin family.
Post-Translational Modification: ISGylated.
Cellular Location: Cytoplasm > Cytoskeleton.

Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Database Links:
  • Entrez Gene: 58?Human
  • Entrez Gene: 11459?Mouse
  • Entrez Gene: 29437?Rat
  • Omim: 102610?Human
  • SwissProt: P68133?Human
  • SwissProt: P68134?Mouse
  • SwissProt: P68136?Rat
  • Unigene: 1288?Human
  • Unigene: 214950?Mouse
  • Unigene: 82732?Rat
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    Synonyms:
  • a actin Antibody
  • ACTA Antibody
  • ACTA1 Antibody
  • Actin Antibody
  • Actin alpha skeletal muscle Antibody
  • actin, alpha 1, skeletal muscle Antibody
  • actin, alpha 1, skeletal muscle 1 Antibody
  • Actin, alpha skeletal muscle Antibody
  • actina Antibody
  • actine Antibody
  • ACTS_HUMAN Antibody
  • aktin Antibody
  • Alpha Actin 1 Antibody
  • alpha skeletal muscle Antibody
  • Alpha skeletal muscle Actin Antibody
  • alpha-actin Antibody
  • Alpha-actin-1 Antibody
  • ASMA Antibody
  • CFTD Antibody
  • CFTD1 Antibody
  • CFTDM Antibody
  • MPFD Antibody
  • NEM1 Antibody
  • NEM2 Antibody
  • NEM3 Antibody
  • nemaline myopathy type 3 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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