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Anti-FTCD Antibody

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产品名称: Anti-FTCD Antibody
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简单介绍

Anti-FTCD Antibody


Anti-FTCD Antibody  的详细介绍
Name: Anti-FTCD Antibody
See all FTCD primary antibodies
Description: Goat polyclonal antibody to FTCD.
Applications: ELISA, WB
Reactivity: Human
Immunogen: Synthetic peptide corresponding to Human FTCD (N terminal).
Sequence: SQLVECVPNFSEGKNQ
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 µg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.
Involvement in Disease: Glutamate formiminotransferase deficiency: Autosomal recessive disorder. Features of a severe phenotype, include elevated levels of formiminoglutamate (FIGLU) in the urine in response to histidine administration, megaloblastic anemia, and mental retardation. Features of a mild phenotype include high urinary excretion of FIGLU in the absence of histidine administration, mild developmental delay, and no hematological abnormalities.
Sequence Similarities: In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family.
Cellular Location: Cytoplasm > Cytoskeleton > Microtubule organizing center > Centrosome > Centriole. Golgi apparatus.

More abundantly located around the mother centriole.
Database Links:
  • Entrez Gene: 10841 Human
  • Omim: 606806 Human
  • SwissProt: O95954 Human
  • Unigene: 415846 Human
    		•
    Synonyms:
  • 58K Golgi protein Antibody
  • Formimidoyltetrahydrofolate cyclodeaminase Antibody
  • Formimidoyltransferase cyclodeaminase Antibody
  • Formiminotetrahydrofolate cyclodeaminase Antibody
  • Formiminotransferase cyclodeaminase Antibody
  • Formiminotransferase-cyclodeaminase Antibody
  • FTCD Antibody
  • FTCD_HUMAN Antibody
  • Glutamate formiminotransferase Antibody
  • Glutamate formyltransferase Antibody
  • LCHC 1 Antibody
  • LCHC1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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