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Anti-NOS1 Antibody

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产品名称: Anti-NOS1 Antibody
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简单介绍

Anti-NOS1 Antibody


Anti-NOS1 Antibody  的详细介绍
Name: Anti-NOS1 Antibody
See all nNOS (neuronal) primary antibodies
Description: Goat polyclonal antibody to NOS1.
Applications: ELISA, WB, IHC
Reactivity: Human
Immunogen: Synthetic peptide corresponding to Human NOS1 (C terminal).
Sequence: C-ESKKDTDEVFSS
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 μg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
Tissue Specificity: Isoform 1 is ubiquitously expressed: detected in skeletal muscle and brain, also in testis, lung and kidney, and at low levels in heart, adrenal gland and retina. Not detected in the platelets. Isoform 3 is expressed only in testis. Isoform 4 is detected in testis, skeletal muscle, lung, and kidney, at low levels in the brain, but not in the heart and adrenal gland.
Sequence Similarities: Belongs to the NOS family.
Post-Translational Modification: Ubiquitinated; mediated by STUB1/CHIP in the presence of Hsp70 and Hsp40 (in vitro).
Cellular Location: Cell membrane > Sarcolemma. Cell projection > Dendritic spine.

In skeletal muscle, it is localized beneath the sarcolemma of fast-twitch muscle fiber by associating with the dystrophin glycoprotein complex. In neurons, enriched in dendritic spines (By similarity).
Database Links:
  • Entrez Gene: 4842?Human
  • Omim: 163731?Human
  • SwissProt: P29475?Human
  • Unigene: 654410?Human
  • Unigene: 684465?Human
  • Unigene: 684466?Human
  • Unigene: 684467?Human
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    Synonyms:
  • 2310005C01Rik Antibody
  • BNOS Antibody
  • Constitutive NOS Antibody
  • EC 1.14.13.39 Antibody
  • IHPS 1 Antibody
  • IHPS1 Antibody
  • N-NOS Antibody
  • NC-NOS Antibody
  • neuronal Nitric Oxide Synthase Antibody
  • Neuronal NOS Antibody
  • Nitric oxide synthase , neuronal, included Antibody
  • Nitric oxide synthase 1 Antibody
  • Nitric oxide synthase 1 (neuronal) Antibody
  • Nitric oxide synthase, brain Antibody
  • Nitric oxide synthase, penile neuronal, included Antibody
  • NNOS Antibody
  • nNOS (neuronal) Antibody
  • NO Antibody
  • NOS Antibody
  • NOS 1 Antibody
  • NOS type I Antibody
  • NOS-I Antibody
  • NOS1 Antibody
  • NOS1_HUMAN Antibody
  • Peptidyl-cysteine S-nitrosylase NOS1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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