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Anti-IL-6 Antibody

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产品名称: Anti-IL-6 Antibody
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简单介绍

Anti-IL-6 Antibody


Anti-IL-6 Antibody  的详细介绍
Name: Anti-IL-6 Antibody
See all IL-6 primary antibodies
Description: Rabbit polyclonal antibody to IL-6
Specificity: IL-6 pAb detects endogenous levels of IL-6 protein.
Applications: WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant full length Human IL-6.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 23 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol.
Function: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.
Involvement in Disease: Rheumatoid arthritis systemic juvenile: An inflammatory articular disorder with systemic-onset beginning before the age of 16. It represents a subgroup of juvenile arthritis associated with severe extraarticular features and occasionally fatal complications. During active phases of the disorder, patients display a typical daily spiking fever, an evanescent macular rash, lymphadenopathy, hepatosplenomegaly, serositis, myalgia and arthritis.
Sequence Similarities: Belongs to the IL-6 superfamily.
Post-Translational Modification: N- and O-glycosylated.
Cellular Location: Secreted.
Database Links:
  • Entrez Gene: 3569?Human
  • Entrez Gene: 16193?Mouse
  • Entrez Gene: 24498?Rat
  • Omim: 147620?Human
  • SwissProt: P05231?Human
  • SwissProt: P08505?Mouse
  • SwissProt: P20607?Rat
  • Unigene: 654458?Human
  • Unigene: 1019?Mouse
  • Unigene: 9873?Rat
    		•
    Synonyms:
  • Interleukin BSF 2 Antibody
  • B cell differentiation factor Antibody
  • B cell stimulatory factor 2 Antibody
  • B-cell stimulatory factor 2 Antibody
  • BSF 2 Antibody
  • BSF-2 Antibody
  • BSF2 Antibody
  • CDF Antibody
  • CTL differentiation factor Antibody
  • Cytotoxic T cell differentiation factor Antibody
  • Hepatocyte stimulating fact Antibody
  • Hepatocyte stimulating factor Antibody
  • Hepatocyte stimulatory factor Antibody
  • HGF Antibody
  • HPGF Antibody
  • HSF Antibody
  • Hybridoma growth factor Antibody
  • Hybridoma growth factor Interferon beta-2 Antibody
  • Hybridoma plasmacytoma growth factor Antibody
  • IFN-beta-2 Antibody
  • IFNB2 Antibody
  • IL 6 Antibody
  • IL-6 Antibody
  • IL6 Antibody
  • IL6 protein Antibody
  • IL6_HUMAN Antibody
  • Interferon beta 2 Antibody
  • Interferon beta-2 Antibody
  • Interleukin 6 Antibody
  • Interleukin 6 (interferon beta 2) Antibody
  • Interleukin BSF 2 Antibody
  • Interleukin BSF2 Antibody
  • Interleukin-6 Antibody
  • Interleukin6 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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