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Anti-DUSP1 Antibody

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产品名称: Anti-DUSP1 Antibody
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简单介绍

Anti-DUSP1 Antibody


Anti-DUSP1 Antibody  的详细介绍
Name: Anti-DUSP1 Antibody
See all DUSP1 primary antibodies
Description: Goat polyclonal antibody to DUSP1.
Applications: ELISA, WB, IHC
Reactivity: Human
Immunogen: Synthetic peptide corresponding to Human DUSP1 (C terminal).
Sequence: SYLQSPITTSPSC
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 μg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.
Tissue Specificity: Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney.
Sequence Similarities: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Post-Translational Modification: Phosphorylation at Ser-359 and Ser-364 by MAPK1/ERK2 and MAPK3/ERK1 reduces its rate of degradation.
Cellular Location: Nucleus.
Database Links:
  • Entrez Gene: 1843?Human
  • Omim: 600714?Human
  • SwissProt: P28562?Human
  • Unigene: 171695?Human
    		•
    Synonyms:
  • CL 100 Antibody
  • CL100 Antibody
  • Dual Specificity Phosphatase 1 Antibody
  • Dual specificity protein phosphatase 1 Antibody
  • Dual specificity protein phosphatase hVH1 Antibody
  • DUS1_HUMAN Antibody
  • DUSP 1 Antibody
  • DUSP1 Antibody
  • HVH1 Antibody
  • MAP kinase phosphatase 1 Antibody
  • Mitogen-activated protein kinase phosphatase 1 Antibody
  • MKP-1 Antibody
  • MKP1 Antibody
  • Protein tyrosine phosphatase CL100 Antibody
  • Protein-tyrosine phosphatase CL100 Antibody
  • PTPN10 Antibody
  • Serine/threonine specific protein phosphatase Antibody
  • VH1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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