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Anti-UBE2I Antibody

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产品名称: Anti-UBE2I Antibody
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简单介绍

Anti-UBE2I Antibody


Anti-UBE2I Antibody  的详细介绍
Name: Anti-UBE2I Antibody
See all UBE2I primary antibodies
Description: Goat polyclonal antibody to UBE2I.
Applications: ELISA, WB, IHC, ICC
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide corresponding to Human UBE2I (N terminal).
Sequence: SGIALSRLAQERK-C
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 μg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Accepts the ubiquitin-like proteins SUMO1, SUMO2 and SUMO3 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451. Can catalyze the formation of poly-SUMO chains. Essential for nuclear architecture and chromosome segregation (By similarity). Necessary for sumoylation of FOXL2 and KAT5. Sumoylates p53/TP53 at 'Lys-386' (By similarity).
Tissue Specificity: Broadly expressed, with highest levels in spleen and lung (at protein level).
Sequence Similarities: Belongs to the ubiquitin-conjugating enzyme family.
Post-Translational Modification: Phosphorylation at Ser-71 significantly enhances SUMOylation activity.
Cellular Location: Nucleus. Cytoplasm.

Mainly nuclear. In spermatocytes, localizes in synaptonemal complexes. Recruited by BCL11A into the nuclear body (By similarity).
Database Links:
  • Entrez Gene: 7329?Human
  • Entrez Gene: 100044900?Mouse
  • Entrez Gene: 22196?Mouse
  • Entrez Gene: 25573?Rat
  • Omim: 601661?Human
  • SwissProt: P63279?Human
  • SwissProt: P63280?Mouse
  • SwissProt: P63281?Rat
  • Unigene: 302903?Human
  • Unigene: 240044?Mouse
  • Unigene: 384234?Mouse
  • Unigene: 442797?Mouse
  • Unigene: 2274?Rat
    		•
    Synonyms:
  • C358B7.1 Antibody
  • p18 Antibody
  • SUMO 1 protein ligase Antibody
  • SUMO conjugating enzyme UBC9 Antibody
  • SUMO-conjugating enzyme UBC9 Antibody
  • SUMO-protein ligase Antibody
  • SUMO1 protein ligase Antibody
  • UBC9 Antibody
  • UBC9_HUMAN Antibody
  • UBCE9 Antibody
  • Ube2i Antibody
  • UBE2I / UBC9 Antibody
  • Ubiquitin carrier protein Antibody
  • Ubiquitin carrier protein 9 Antibody
  • Ubiquitin carrier protein I Antibody
  • Ubiquitin conjugating enzyme 9 Antibody
  • Ubiquitin conjugating enzyme E2I (homologous to yeast UBC9) Antibody
  • Ubiquitin conjugating enzyme E2I (UBC9 homolog, yeast) Antibody
  • Ubiquitin conjugating enzyme UbcE2A Antibody
  • Ubiquitin like protein SUMO 1 conjugating enzyme Antibody
  • Ubiquitin protein ligase E2I Antibody
  • Ubiquitin-conjugating enzyme E2 I Antibody
  • Ubiquitin-protein ligase I Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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