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Anti-PTBP1 Antibody

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产品名称: Anti-PTBP1 Antibody
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简单介绍

Anti-PTBP1 Antibody


Anti-PTBP1 Antibody  的详细介绍
Name: Anti-PTBP1 Antibody
See all PTBP1 primary antibodies
Description: Goat polyclonal antibody to PTBP1.
Applications: ELISA, WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide corresponding to Human PTBP1 (N terminal).
Sequence: DGIVPDIAVGTKR-C
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 μg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10 (By similarity).
Cellular Location: Nucleus.
Database Links:
  • Entrez Gene: 5725?Human
  • Entrez Gene: 19205?Mouse
  • Entrez Gene: 29497?Rat
  • Omim: 600693?Human
  • SwissProt: P26599?Human
  • SwissProt: P17225?Mouse
  • SwissProt: Q00438?Rat
  • Unigene: 172550?Human
  • Unigene: 265610?Mouse
  • Unigene: 472059?Mouse
  • Unigene: 64440?Rat
    		•
    Synonyms:
  • 57 kDa RNA binding protein PPTB 1 Antibody
  • 57 kDa RNA-binding protein PPTB-1 Antibody
  • Heterogeneous nuclear ribonucleoprotein I Antibody
  • Heterogeneous Nuclear Ribonucleoprotein Polypeptide I Antibody
  • hnRNP I Antibody
  • HNRNP-I Antibody
  • HNRNPI Antibody
  • HNRPI Antibody
  • MGC10830 Antibody
  • MGC8461 Antibody
  • Polypyrimidine tract binding protein Antibody
  • Polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) Antibody
  • Polypyrimidine Tract Binding Protein 1 Antibody
  • Polypyrimidine tract-binding protein 1 Antibody
  • pPTB Antibody
  • PTB Antibody
  • PTB 1 Antibody
  • PTB 2 Antibody
  • PTB 3 Antibody
  • PTB 4 Antibody
  • PTB T Antibody
  • PTB1 Antibody
  • PTB2 Antibody
  • PTB3 Antibody
  • PTB4 Antibody
  • PTBP 1 Antibody
  • PTBP1 Antibody
  • PTBP1_HUMAN Antibody
  • PTBT Antibody
  • RNA Binding Protein Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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