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Anti-DiMethyl-Histone H3-K27 Antibody

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产品名称: Anti-DiMethyl-Histone H3-K27 Antibody
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简单介绍

Anti-DiMethyl-Histone H3-K27 Antibody


Anti-DiMethyl-Histone H3-K27 Antibody  的详细介绍
Name: Anti-DiMethyl-Histone H3-K27 Antibody
See all Histone H3 primary antibodies
Description: Rabbit polyclonal antibody to DiMethyl-Histone H3-K27.
Applications: WB, IHC, IF, IP, ChIP, ChIPseq
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200, IP: 1:50 - 1:200, ChIP: 1:20 - 1:100, ChIP seq: 1:20 - 1:100.
Reactivity: Human, Mouse, Rat
Immunogen: A synthetic methylated peptide corresponding to residues surrounding K27 of human histone H3.
Protein Length: 136
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Tissue Specificity: Expressed in testicular cells.
Sequence Similarities: Belongs to the histone H3 family.
Post-Translational Modification: Acetylation is generally linked to gene activation. Acetylation on Lys-10 (H3K9ac) impairs methylation at Arg-9 (H3R8me2s). Acetylation on Lys-19 (H3K18ac) and Lys-24 (H3K24ac) favors methylation at Arg-18 (H3R17me). Acetylation at Lys-123 (H3K122ac) by EP300/p300 plays a central role in chromatin structure: localizes at the surface of the histone octamer and stimulates transcription, possibly by promoting nucleosome instability (By similarity).
Cellular Location: Nucleus. Chromosome.
Database Links:
  • Entrez Gene: 10338?Human
  • Entrez Gene: 3020?Human
  • Entrez Gene: 3021?Human
  • Entrez Gene: 8290?Human
  • Entrez Gene: 8350?Human
  • Entrez Gene: 8351?Human
  • Entrez Gene: 8352?Human
  • Entrez Gene: 8353?Human
  • Entrez Gene: 8354?Human
  • Entrez Gene: 8355?Human
  • Entrez Gene: 8356?Human
  • Entrez Gene: 8357?Human
  • Entrez Gene: 8358?Human
  • Entrez Gene: 8968?Human
  • Entrez Gene: 15078?Mouse
  • Entrez Gene: 15079?Mouse
  • Entrez Gene: 15080?Mouse
  • Entrez Gene: 15081?Mouse
  • Entrez Gene: 260423?Mouse
  • Entrez Gene: 319148?Mouse
  • Entrez Gene: 319149?Mouse
  • Entrez Gene: 319150?Mouse
  • Entrez Gene: 319151?Mouse
  • Entrez Gene: 319152?Mouse
  • Entrez Gene: 319153?Mouse
  • Entrez Gene: 360198?Mouse
  • Entrez Gene: 97908?Mouse
  • Entrez Gene: 100361558?Rat
  • Entrez Gene: 100364501?Rat
  • Entrez Gene: 100365096?Rat
  • Entrez Gene: 100365669?Rat
  • Entrez Gene: 117056?Rat
  • Entrez Gene: 289314?Rat
  • Entrez Gene: 291159?Rat
  • Entrez Gene: 314977?Rat
  • Entrez Gene: 364716?Rat
  • Entrez Gene: 679950?Rat
  • Entrez Gene: 679994?Rat
  • Entrez Gene: 680511?Rat
  • Entrez Gene: 680599?Rat
  • Entrez Gene: 682330?Rat
  • Entrez Gene: 691496?Rat
  • Omim: 601058?Human
  • Omim: 601128?Human
  • Omim: 602810?Human
  • Omim: 602811?Human
  • Omim: 602812?Human
  • Omim: 602813?Human
  • Omim: 602814?Human
  • Omim: 602815?Human
  • Omim: 602816?Human
  • Omim: 602817?Human
  • Omim: 602818?Human
  • Omim: 602819?Human
  • SwissProt: P06351?Human
  • SwissProt: P16106?Human
  • SwissProt: P68431?Human
  • SwissProt: P84243?Human
  • SwissProt: Q16695?Human
  • SwissProt: Q6NXT2?Human
  • SwissProt: Q71DI3?Human
  • SwissProt: Q93081?Human
  • SwissProt: P16105?Mouse
  • SwissProt: P68433?Mouse
  • SwissProt: P84228?Mouse
  • SwissProt: P84244?Mouse
  • SwissProt: B0BMY8?Rat
  • SwissProt: P06351?Rat
  • SwissProt: P84245?Rat
  • SwissProt: Q6LED0?Rat
  • Unigene: 132854?Human
  • Unigene: 180877?Human
  • Unigene: 181307?Human
  • Unigene: 247813?Human
  • Unigene: 247814?Human
  • Unigene: 248171?Human
  • Unigene: 248176?Human
  • Unigene: 443021?Human
  • Unigene: 484990?Human
  • Unigene: 532144?Human
  • Unigene: 533292?Human
  • Unigene: 533624?Human
  • Unigene: 546315?Human
  • Unigene: 586261?Human
  • Unigene: 591778?Human
  • Unigene: 626666?Human
  • Unigene: 726012?Human
  • Unigene: 138832?Mouse
  • Unigene: 18516?Mouse
  • Unigene: 221301?Mouse
  • Unigene: 221389?Mouse
  • Unigene: 261657?Mouse
  • Unigene: 261658?Mouse
  • Unigene: 262517?Mouse
  • Unigene: 315189?Mouse
  • Unigene: 316825?Mouse
  • Unigene: 322735?Mouse
  • Unigene: 347699?Mouse
  • Unigene: 371563?Mouse
  • Unigene: 377874?Mouse
  • Unigene: 390558?Mouse
  • Unigene: 397328?Mouse
  • Unigene: 442502?Mouse
  • Unigene: 106155?Rat
  • Unigene: 124815?Rat
  • Unigene: 138090?Rat
  • Unigene: 198918?Rat
  • Unigene: 230771?Rat
  • Unigene: 29857?Rat
    		•
    Synonyms:
  • H3.3A Antibody
  • HIST1 cluster, H3E Antibody
  • HIST1 cluster, H3J Antibody
  • Histone gene cluster 1, H3 histone family, member E Antibody
  • Histone gene cluster 1, H3G Antibody
  • H3 histone family, member A Antibody
  • H3 histone family, member J Antibody
  • H3.1 Antibody
  • H3/l Antibody
  • H3F3 Antibody
  • H3FF Antibody
  • H3FJ Antibody
  • H3FL Antibody
  • HIST1 cluster, H3E Antibody
  • HIST1 cluster, H3I Antibody
  • Histone gene cluster 1, H3 histone family, member E Antibody
  • Histone gene cluster 1, H3C Antibody
  • histone H3.1t Antibody
  • Histone H3/o Antibody
  • Cit Histone H3 Antibody
  • Citrullated Antibody
  • citrullin Antibody
  • Citrullinated Histone H3 Antibody
  • citrulline Antibody
  • FLJ92264 Antibody
  • H 3 Antibody
  • H3 Antibody
  • H3 3 like sequence MH921 Antibody
  • H3 3A Antibody
  • H3 a Antibody
  • H3 b Antibody
  • H3 c Antibody
  • H3 d Antibody
  • H3 f Antibody
  • H3 h Antibody
  • H3 histone Antibody
  • H3 histone family member E pseudogene Antibody
  • H3 histone family, member A Antibody
  • H3 histone family, member B Antibody
  • H3 histone family, member C Antibody
  • H3 histone family, member D Antibody
  • H3 histone family, member F Antibody
  • H3 histone family, member H Antibody
  • H3 histone family, member I Antibody
  • H3 histone family, member J Antibody
  • H3 histone family, member K Antibody
  • H3 histone family, member L Antibody
  • H3 histone family, member T Antibody
  • H3 histone, family 3A Antibody
  • H3 i Antibody
  • H3 j Antibody
  • H3 k Antibody
  • H3 l Antibody
  • H3.1 Antibody
  • H3.3A Antibody
  • H3/A Antibody
  • H3/b Antibody
  • H3/c Antibody
  • H3/d Antibody
  • h3/f Antibody
  • H3/h Antibody
  • H3/i Antibody
  • H3/j Antibody
  • H3/k Antibody
  • H3/l Antibody
  • H3/t Antibody
  • H31_HUMAN Antibody
  • H33_HUMAN Antibody
  • H3F1K Antibody
  • H3F3 Antibody
  • H3F3A Antibody
  • H3f3b Antibody
  • H3FA Antibody
  • H3FB Antibody
  • H3FC Antibody
  • H3FD Antibody
  • H3FF Antibody
  • H3FH Antibody
  • H3FI Antibody
  • H3FJ Antibody
  • H3FK Antibody
  • H3FL Antibody
  • HIST1 cluster, H3A Antibody
  • HIST1 cluster, H3B Antibody
  • HIST1 cluster, H3C Antibody
  • HIST1 cluster, H3D Antibody
  • HIST1 cluster, H3F Antibody
  • HIST1 cluster, H3G Antibody
  • HIST1 cluster, H3H Antibody
  • HIST1 cluster, H3I Antibody
  • HIST1 cluster, H3J Antibody
  • Hist1h3a Antibody
  • HIST1H3B Antibody
  • HIST1H3C Antibody
  • HIST1H3D Antibody
  • HIST1H3E Antibody
  • HIST1H3F Antibody
  • HIST1H3G Antibody
  • HIST1H3H Antibody
  • HIST1H3I Antibody
  • HIST1H3J Antibody
  • HIST3H3 Antibody
  • HIST3HA Antibody
  • histone 1, H3a Antibody
  • Histone 1, H3b Antibody
  • Histone 1, H3c Antibody
  • Histone 1, H3d Antibody
  • Histone 1, H3e Antibody
  • Histone 1, H3f Antibody
  • Histone 1, H3g Antibody
  • Histone 1, H3h Antibody
  • Histone 1, H3i Antibody
  • Histone 1, H3j Antibody
  • Histone 3, H3 Antibody
  • histone cluster 1 H3 family member a Antibody
  • histone cluster 1 H3 family member b Antibody
  • histone cluster 1 H3 family member c Antibody
  • histone cluster 1 H3 family member d Antibody
  • histone cluster 1 H3 family member e Antibody
  • histone cluster 1 H3 family member f Antibody
  • histone cluster 1 H3 family member g Antibody
  • histone cluster 1 H3 family member h Antibody
  • histone cluster 1 H3 family member i Antibody
  • histone cluster 1 H3 family member j Antibody
  • Histone cluster 1, H3a Antibody
  • Histone cluster 1, H3b Antibody
  • Histone cluster 1, H3c Antibody
  • Histone cluster 1, H3d Antibody
  • Histone cluster 1, H3e Antibody
  • Histone cluster 1, H3f Antibody
  • Histone cluster 1, H3g Antibody
  • Histone cluster 1, H3i Antibody
  • Histone cluster 1, H3j Antibody
  • Histone gene cluster 1, H3 histone family, member A Antibody
  • Histone gene cluster 1, H3 histone family, member B Antibody
  • Histone gene cluster 1, H3 histone family, member C Antibody
  • Histone gene cluster 1, H3 histone family, member D Antibody
  • Histone gene cluster 1, H3 histone family, member F Antibody
  • Histone gene cluster 1, H3 histone family, member G Antibody
  • Histone gene cluster 1, H3 histone family, member H Antibody
  • Histone gene cluster 1, H3 histone family, member I Antibody
  • Histone gene cluster 1, H3 histone family, member J Antibody
  • Histone gene cluster 1, H3A Antibody
  • Histone gene cluster 1, H3B Antibody
  • Histone gene cluster 1, H3C Antibody
  • Histone gene cluster 1, H3D Antibody
  • Histone gene cluster 1, H3E Antibody
  • Histone gene cluster 1, H3F Antibody
  • Histone gene cluster 1, H3G Antibody
  • Histone gene cluster 1, H3H Antibody
  • Histone gene cluster 1, H3I Antibody
  • Histone gene cluster 1, H3J Antibody
  • Histone H 3 Antibody
  • Histone H3 Antibody
  • Histone H3 3 pseudogene Antibody
  • Histone H3 Citrullated Antibody
  • Histone H3.1 Antibody
  • Histone H3.1t Antibody
  • Histone H3.2 Antibody
  • Histone H3.3 Antibody
  • Histone H3.3C Antibody
  • Histone H3.5 Antibody
  • Histone H3/a Antibody
  • Histone H3/b Antibody
  • Histone H3/c Antibody
  • Histone H3/d Antibody
  • Histone H3/f Antibody
  • Histone H3/h Antibody
  • Histone H3/i Antibody
  • Histone H3/j Antibody
  • Histone H3/k Antibody
  • Histone H3/l Antibody
  • Histone H3/m Antibody
  • Histone H3/o Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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