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Anti-CD13 Antibody

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产品名称: Anti-CD13 Antibody
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简单介绍

Anti-CD13 Antibody


Anti-CD13 Antibody  的详细介绍
Name: Anti-CD13 Antibody
See all CD13 primary antibodies
Description: Mouse monoclonal (WM15) antibody to CD13.
Specificity: The antibody WM15 recognises the human CD13 cell surface glycoprotein, a 150 kDa molecule expressed on granulocytes, endothelial cells, epithelial cells and myeloid progenitors.
Applications: FC, IP, IHC-Fr, FUNC
Reactivity: Human, Non-Human Primates
Immunogen: Human AML cells.
Host: Mouse
Clonality: Monoclonal
Clone: WM15
Isotype: IgG1
Conjugate: Unconjugated
Purification: Protein A chromatography.
Concentration: 1 mg/ml
Purity: > 95% (by SDS-PAGE)
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.4, with 15mM Sodium Azide.
Storage: Store at 2-8°C.
Function: Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization.
Tissue Specificity: Expressed in epithelial cells of the kidney, intestine, and respiratory tract; granulocytes, monocytes, fibroblasts, endothelial cells, cerebral pericytes at the blood-brain barrier, synaptic membranes of cells in the CNS. Also expressed in endometrial stromal cells, but not in the endometrial glandular cells. Found in the vasculature of tissues that undergo angiogenesis and in malignant gliomas and lymph node metastases from multiple tumor types but not in blood vessels of normal tissues. A soluble form has been found in plasma. It is found to be elevated in plasma and effusions of cancer patients.
Sequence Similarities: Belongs to the peptidase M1 family.
Post-Translational Modification: Sulfated.
Cellular Location: Cell membrane.

Also found as a soluble form.
Database Links:
  • Entrez Gene: 290?Human
  • Omim: 151530?Human
  • SwissProt: P15144?Human
  • Unigene: 1239?Human
    		•
    Synonyms:
  • Alanyl (membrane) aminopeptidase Antibody
  • Alanyl aminopeptidase Antibody
  • Aminopeptidase M Antibody
  • Aminopeptidase N Antibody
  • AMPN_HUMAN Antibody
  • ANPEP Antibody
  • AP M Antibody
  • AP N Antibody
  • AP-M Antibody
  • AP-N Antibody
  • APN Antibody
  • CD 13 Antibody
  • CD13 Antibody
  • CD13 antigen Antibody
  • gp150 Antibody
  • hAPN Antibody
  • LAP 1 Antibody
  • LAP1 Antibody
  • Microsomal aminopeptidase Antibody
  • Myeloid plasma membrane glycoprotein CD13 Antibody
  • p150 Antibody
  • PEPN Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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