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Anti-AIF1 Antibody

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产品名称: Anti-AIF1 Antibody
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简单介绍

Anti-AIF1 Antibody


Anti-AIF1 Antibody  的详细介绍
Name: Anti-AIF1 Antibody
See all AIF1 primary antibodies
Description: Goat polyclonal antibody to AIF1.
Applications: ELISA, WB, IHC
Reactivity: Human, Mouse
Immunogen: Synthetic peptide corresponding to Human AIF1 (internal region).
Sequence: C-NKQFLDDPKYSSDED
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 μg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
Tissue Specificity: Abundantly expressed in the testis, moderately in the spleen and lymph nodes and at low levels in the liver and thymus. Detected in macrophages.
Post-Translational Modification: Phosphorylated on serine residues.
Cellular Location: Cytoplasm > Cytoskeleton. Cell projection > Ruffle membrane. Cell projection > Phagocytic cup.

Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.
Database Links:
  • Entrez Gene: 199?Human
  • Entrez Gene: 11629?Mouse
  • Omim: 601833?Human
  • SwissProt: P55008?Human
  • SwissProt: O70200?Mouse
  • Unigene: 76364?Human
  • Unigene: 10747?Mouse
    		•
    Synonyms:
  • AIF 1 Antibody
  • AIF-1 Antibody
  • Aif1 Antibody
  • AIF1 protein Antibody
  • AIF1_HUMAN Antibody
  • Allograft inflammatory factor 1 Antibody
  • Allograft inflammatory factor 1 splice variant G Antibody
  • allograft inflammatory factor-1 splice variant Hara-1 Antibody
  • balloon angioplasty responsive transcription Antibody
  • BART 1 Antibody
  • G1 Antibody
  • G1 putative splice variant of allograft inflamatory factor 1 Antibody
  • IBA 1 Antibody
  • Iba1 Antibody
  • interferon gamma responsive transcript Antibody
  • Interferon responsive transcript 1 Antibody
  • interferon responsive transcript factor 1 Antibody
  • Ionized calcium binding adapter molecule 1 Antibody
  • ionized calcium-binding adapter molecule Antibody
  • Ionized calcium-binding adapter molecule 1 Antibody
  • IRT 1 Antibody
  • IRT1 Antibody
  • Microglia response factor Antibody
  • MRF1 Antibody
  • Protein g1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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