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Anti-CD73 Antibody

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产品名称: Anti-CD73 Antibody
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简单介绍

Anti-CD73 Antibody


Anti-CD73 Antibody  的详细介绍
Name: Anti-CD73 Antibody
See all CD73 primary antibodies
Description: Mouse monoclonal (AD2) antibody to CD73.
Specificity: The mouse monoclonal antibody AD2 recognizes CD73, a 70 kDa GPI-anchored 5´-nucleotidase expressed predominantly on T and B cell subsets, follicular dendritic cells and endothelial cells.
Applications: FC
Reactivity: Human
Host: Mouse
Clonality: Monoclonal
Clone: AD2
Isotype: IgG1
Conjugate: Unconjugated
Purification: Protein A chromatography.
Concentration: 1 mg/ml
Purity: > 95% (by SDS-PAGE)
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.4, with 15mM Sodium Azide.
Storage: Store at 2-8°C.
Function: Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities.
Involvement in Disease: Calcification of joints and arteries: A condition characterized by *****-onset calcification of the lower extremity arteries, including the iliac, femoral and tibial arteries, and hand and foot capsule joints. Age of onset has been reported as early as the second decade of life, usually involving intense joint pain or calcification in the hands.
Sequence Similarities: Belongs to the 5'-nucleotidase family.
Cellular Location: Cell membrane.
Database Links:
  • Entrez Gene: 4907 Human
  • Omim: 129190 Human
  • SwissProt: P21589 Human
  • Unigene: 153952 Human
  • Synonyms:
  • 5' NT Antibody
  • 5' nucleotidase (CD73) Antibody
  • 5' nucleotidase precursor Antibody
  • 5' nucleotidase, ecto Antibody
  • 5' nucleotidase, ecto (CD73) Antibody
  • 5'-NT Antibody
  • 5'-nucleotidase Antibody
  • 5NTD_HUMAN Antibody
  • CD73 Antibody
  • CD73 antigen Antibody
  • E5NT Antibody
  • Ecto 5' nucleotidase Antibody
  • Ecto-5'-nucleotidase Antibody
  • eN Antibody
  • eNT Antibody
  • NT Antibody
  • NT5 Antibody
  • NT5E Antibody
  • NTE Antibody
  • Purine 5 Prime Nucleotidase Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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