首页
品牌
ELISA试剂盒
抗体抗原
公司新闻
技术文章
关于拜力
留言询价
产品资料
首页
>>>
产品目录
>>>
中国授权代理品牌
>>> 
Antibodies
Anti-CD11a Antibody
点击看大图
如果您对该产品感兴趣的话,可以
产品名称:
Anti-CD11a Antibody
产品型号:
产品展商:
其它品牌
产品文档:
无相关文档
简单介绍
Anti-CD11a
Antibody
Anti-CD11a Antibody
的详细介绍
Overview
Name:
Anti-CD11a
Antibody
See all CD11a primary antibodies
Description:
Mouse monoclonal (MEM-25) antibody to CD11a.
Specificity:
The antibody MEM-25 reacts with CD11a (alpha subunit of human LFA-1), a 170-180 kDa type I transmembrane glycoprotein expressed on B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils.
Applications:
FC, IP, FUNC
Reactivity:
Human
Immunogen:
Leukocytes from a patient suffering from a LGL Type leukemia.
Host:
Mouse
Clonality:
Monoclonal
Clone:
MEM-25
Isotype:
IgG1
Conjugate:
Unconjugated
Purification:
Protein A chromatography.
Concentration:
1 mg/ml
Purity:
> 95% (by SDS-PAGE)
Product Form:
Liquid
Formulation:
Supplied in Phosphate Buffered Saline, pH 7.4, without Azide (0.2 µm filter sterilised). Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
Storage:
Store at 2-8°C.
Target
Function:
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin alpha-L/beta-2 is also a receptor for F11R (PubMed:11812992, PubMed:15528364). Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity (PubMed:15356110). Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed:11812992). Required for generation of common lymphoid progenitor cells in bone marrow, indicating a role in lymphopoiesis (By similarity). Integrin alpha-L/beta-2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590).
Tissue Specificity:
Leukocytes.
Sequence Similarities:
Belongs to the integrin alpha chain family.
Post-Translational Modification:
In resting T-cells, up to 40% of surface ITGAL is constitutively phosphorylated. Phosphorylation causes conformational changes needed for ligand binding and is necessary for activation by some physiological agents.
Cellular Location:
Cell membrane.
Database Links:
Entrez Gene: 3683 Human
Omim: 153370 Human
SwissProt: P20701 Human
Unigene: 174103 Human
Synonyms:
Lymphocyte function associated antigen, type 1, alpha subunit Antibody
Antigen CD11A Antibody
Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide Antibody
CD 11a Antibody
CD11 antigen-like family member A Antibody
CD11a Antibody
CD11a antigen Antibody
Integrin Alpha L Antibody
Integrin alpha-L Antibody
Integrin gene promoter Antibody
Integrin, alpha L (antigen CD11A (p180), lymphocyte function associated antigen 1; alpha polypeptide) Antibody
ITAL_HUMAN Antibody
Itgal Antibody
ITGAL protein Antibody
Leukocyte adhesion glycoprotein LFA 1 alpha chain Antibody
Leukocyte adhesion glycoprotein LFA-1 alpha chain Antibody
Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain Antibody
Leukocyte function associated molecule 1 alpha chain Antibody
Leukocyte function-associated molecule 1 alpha chain Antibody
LFA 1 Antibody
LFA 1 alpha Antibody
LFA 1 alpha (LFA1A) Antibody
LFA 1A Antibody
LFA-1A Antibody
LFA1A Antibody
Ly15 Antibody
Ly21 Antibody
Lymphocyte function associated antigen 1 Antibody
Lymphocyte Function Associated Antigen Type 1 alpha Antibody
lymphocyte function-associated antigen 1, alpha polypeptide Antibody
p180 Antibody
Information:
Target information shown above is from the UniProt Consortium.
产品留言
标题
联系人
联系电话
内容
验证码
点击换一张
注:1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!
相关产品
Anti-Fer Antibody
Anti-FER (Phospho-Tyr402) Antibody
Anti-FEN1 Antibody
Anti-FEN1 Antibody
Anti-FEN1 (A119) Antibody
Anti-FEN1 (7H8) Antibody
Anti-FEN-1 Antibody
Anti-FEM1B Antibody
Anti-FEM1A Antibody
Anti-FEM1A Antibody
Anti-FDXR Antibody
Anti-FDPS Antibody
Anti-FDPS Antibody
Anti-FDFT1 Antibody
Anti-FDFT1 Antibody
Anti-FDCSP Antibody
Anti-FCRL4 Antibody
Anti-FCHO1 Antibody
Anti-FCGR3A Antibody
Anti-FCGR2B Antibody
Anti-FCGR2A Antibody
Anti-FCGR2A Antibody
Anti-FCER2 Antibody
Anti-FCER1A Antibody
Anti-FCAR Antibody
Anti-FBXW7 Antibody
Anti-FBXW4 Antibody
Anti-FBXW12 Antibody
Anti-FBXO44 Antibody
Anti-FBXO44 Antibody
Copyright@ 2003-2024
上海拜力生物科技有限公司
版权所有
本公司网站所展示销售的产品仅供科研!
沪ICP备08023583号-12
沪公网安备 31011202007337号