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Anti-Blood Group Lewis b Antibody

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产品名称: Anti-Blood Group Lewis b Antibody
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Anti-Blood Group Lewis b Antibody


Anti-Blood Group Lewis b Antibody  的详细介绍
Name: Anti-Blood Group Lewis b Antibody
See all Blood Group Lewis b primary antibodies
Description: Mouse monoclonal (2-25LE) antibody to Blood Group Lewis b.
Specificity: The antibody 2-25LE reacts with Lewisb blood group antigen, a carbohydrate determinant carried on both glycolipids and glycoproteins, detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals.
Applications: IHC-P, WB, ELISA
Reactivity: Human
Immunogen: Mucin isolated by size exclusion chromatography from an ovarian cyst fluid (pure endocervical type according to the Fenoglio′s classification).
Host: Mouse
Clonality: Monoclonal
Clone: 2-25LE
Isotype: IgG1
Conjugate: Unconjugated
Purification: Protein A chromatography.
Concentration: 1 mg/ml
Purity: > 95% (by SDS-PAGE)
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.4, with 15mM Sodium Azide.
Storage: Store at 2-8°C.
Function: Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system.
Tissue Specificity: Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum.
Post-Translational Modification: C-, O- and N-glycosylated. O-glycosylated on the Thr-/Ser-rich tandem repeats. C-mannosylation in the Cys-rich subdomains may be required for proper folding of these regions and for export from the endoplasmic reticulum during biosynthesis.
Cellular Location: Secreted.
Database Links:
  • Entrez Gene: 4586?Human
  • SwissProt: P98088?Human
  • Unigene: 534332?Human
  • Unigene: 558950?Human
  • Unigene: 721515?Human
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    Synonyms:
  • Blood Group Lewis b Antibody
  • gastric mucin Antibody
  • leB Antibody
  • lewis antigen system Antibody
  • lewis b Antibody
  • lewis B blood group antigen Antibody
  • lewisb Antibody
  • major airway glycoprotein Antibody
  • MUC5 Antibody
  • mucin 5, subtypes A and C, tracheobronchial/gastric Antibody
  • mucin 5AC, oligomeric mucus/gel-forming Antibody
  • mucin 5AC, oligomeric mucus/gel-forming pseudogene Antibody
  • mucin-5 subtype AC, tracheobronchial Antibody
  • TBM Antibody
  • tracheobronchial mucin Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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