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Anti-VDAC2 Antibody

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产品名称: Anti-VDAC2 Antibody
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简单介绍

Anti-VDAC2 Antibody


Anti-VDAC2 Antibody  的详细介绍
Name: Anti-VDAC2 Antibody
See all VDAC2 primary antibodies
Description: Goat polyclonal antibody to VDAC2.
Applications: ELISA, WB
Reactivity: Human
Immunogen: Synthetic peptide corresponding to Human VDAC2 (C terminal).
Sequence: C-GHKVGLALELEA
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 µg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective.
Tissue Specificity: Expressed in all tissues examined.
Sequence Similarities: Belongs to the eukaryotic mitochondrial porin family.
Post-Translational Modification: Ubiquitinated by PARK2 during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30.
Cellular Location: Mitochondrion outer membrane.
Database Links:
  • Entrez Gene: 7417 Human
  • Omim: 193245 Human
  • SwissProt: P45880 Human
  • Unigene: 355927 Human
    		•
    Synonyms:
  • B-36 vdac Antibody
  • FLJ23841 Antibody
  • hVDAC2 Antibody
  • OTTHUMP00000019878 Antibody
  • OTTHUMP00000019879 Antibody
  • OTTHUMP00000019880 Antibody
  • Outer mitochondrial membrane protein porin 2 Antibody
  • POR Antibody
  • Porin-2 Antibody
  • VDAC 2 Antibody
  • VDAC-2 Antibody
  • VDAC2 Antibody
  • VDAC2_HUMAN Antibody
  • Vdac6 Antibody
  • Voltage dependent anion channel 2 Antibody
  • Voltage dependent anion selective channel protein 2 Antibody
  • Voltage-dependent anion-selective channel protein 2 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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