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Anti-NUMB Antibody

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产品名称: Anti-NUMB Antibody
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简单介绍

Anti-NUMB Antibody


Anti-NUMB Antibody  的详细介绍
Name: Anti-NUMB Antibody
See all NUMB primary antibodies
Description: Goat polyclonal antibody to NUMB.
Applications: ELISA, WB, ICC, IP
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide corresponding to Human NUMB (C terminal).
Sequence: C-PFSSDLQKTFEIEL
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 µg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage (By similarity).
Post-Translational Modification: Phosphorylated on Ser-275 and Ser-294 by CaMK1.
Cellular Location: Membrane.
Database Links:
  • Entrez Gene: 8650 Human
  • Entrez Gene: 18222 Mouse
  • Entrez Gene: 29419 Rat
  • Omim: 603728 Human
  • SwissProt: P49757 Human
  • SwissProt: Q9QZS3 Mouse
  • SwissProt: Q2LC84 Rat
  • Unigene: 654609 Human
  • Unigene: 714879 Human
  • Unigene: 4390 Mouse
  • Unigene: 102078 Rat
    		•
    Synonyms:
  • C14orf41 Antibody
  • c14_5527 Antibody
  • FLJ31314 Antibody
  • h Numb Antibody
  • h-Numb Antibody
  • NUMB Antibody
  • Numb homolog Antibody
  • Numb homolog (Drosophila) Antibody
  • Numb protein homolog Antibody
  • NUMB_HUMAN Antibody
  • Protein numb homolog Antibody
  • Protein S171 Antibody
  • S171 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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