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Antibodies
Anti-STRO-1 Antibody
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产品名称:
Anti-STRO-1 Antibody
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简单介绍
Anti-STRO-1
Antibody
Anti-STRO-1 Antibody
的详细介绍
Overview
Name:
Anti-STRO-1
Antibody
See all STRO-1 primary antibodies
Description:
Mouse monoclonal (STRO-1) antibody to STRO-1.
Specificity:
The mouse monoclonal antibody STRO-1 recognizes the cell surface antigen STRO-1 expressed by bone marrow mesenchymal stromal cells and nucleated erythroid precursors, but not by committed hematopoietic progenitors.
Applications:
FC, ICC
Reactivity:
Human
Immunogen:
Human CD34 positive bone marrow cells.
Host:
Mouse
Clonality:
Monoclonal
Clone:
STRO-1
Isotype:
IgM
Conjugate:
Unconjugated
Purification:
Purified from cell culture supernatant by precipitation and ion exchange chromatography.
Concentration:
1 mg/ml
Purity:
> 95% (by SDS-PAGE)
Product Form:
Liquid
Formulation:
Supplied in Tris Buffered Saline, pH 8.0, with 15mM Sodium Azide.
Storage:
Store at 2-8°C.
Target
Introduction:
STRO-1 is a cell surface antigen expressed by stromal elements in human bone marrow, identified by monoclonal antibody STRO-1. Approximately 10% of mononuclear cells, greater than 95% of which are nucleated erythroid precursors, are STRO-1 positive, whereas the CFU-GM (colony-forming unit granulocyte-macrophage), BFU-E (erythroid burst) and CFU-Mix (mixed colonies) committed progenitor cells are negative. CFU-F (fibroblast colony-forming cells) are present exclusively in the STRO-1 positive population. When plated under long-term bone marrow culture conditions, STRO-1 positive cells generate adherent cell layers containing multiple stromal cell types, including adipocytes, smooth muscle cells, osteoblasts, chondrocytes, and fibroblastic elements. In combination with glycophorin A, STRO-1 is a useful marker for identification of mesenchymal stem cells. STRO-1 and CD117 are markers for osteosarcoma cells.
Synonyms:
STRO-1 Antibody
STRO1 Antibody
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