产品资料

Anti-MMP9 (W680) Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-MMP9 (W680) Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-MMP9 (W680) Antibody


Anti-MMP9 (W680) Antibody  的详细介绍
Name: Anti-MMP9 (W680) Antibody
See all MMP9 primary antibodies
Description: Rabbit polyclonal antibody to MMP9 (W680)
Specificity: MMP9 (W680) pAb detects endogenous levels of MMP9 protein.
Applications: WB, IHC, IF
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 650-700 of Human MMP9.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 92 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Function: May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
Tissue Specificity: Produced by normal alveolar macrophages and granulocytes.
Involvement in Disease: Intervertebral disc disease: A common musculo-skeletal disorder caused by degeneration of intervertebral disks of the lumbar spine. It results in low-back pain and unilateral leg pain.

Metaphyseal anadysplasia 2: A bone development disorder characterized by skeletal anomalies that resolve spontaneously with age. Clinical characteristics are evident from the first months of life and include slight shortness of stature and a mild varus deformity of the legs. Patients attain a normal stature in adolescence and show improvement or complete resolution of varus deformity of the legs and rhizomelic micromelia.
Sequence Similarities: Belongs to the peptidase M10A family.
Post-Translational Modification: Processing of the precursor yields different active forms of 64, 67 and 82 kDa. Sequentially processing by MMP3 yields the 82 kDa matrix metalloproteinase-9.
Cellular Location: Secreted > Extracellular space > Extracellular matrix.
Database Links:
  • Entrez Gene: 4318?Human
  • Entrez Gene: 17395?Mouse
  • Entrez Gene: 81687?Rat
  • Omim: 120361?Human
  • SwissProt: P14780?Human
  • SwissProt: P41245?Mouse
  • SwissProt: P50282?Rat
  • Unigene: 297413?Human
  • Unigene: 4406?Mouse
  • Unigene: 10209?Rat
    		•
    Synonyms:
  • 82 kDa matrix metalloproteinase-9 Antibody
  • 92 kDa gelatinase Antibody
  • 92 kDa type IV collagenase Antibody
  • CLG 4B Antibody
  • CLG4B Antibody
  • Collagenase Type 4 beta Antibody
  • Collagenase type IV 92 KD Antibody
  • EC 3.4.24.35 Antibody
  • Gelatinase 92 KD Antibody
  • Gelatinase B Antibody
  • Gelatinase beta Antibody
  • GelatinaseB Antibody
  • GELB Antibody
  • Macrophage gelatinase Antibody
  • MANDP2 Antibody
  • Matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) Antibody
  • Matrix Metalloproteinase 9 Antibody
  • MMP 9 Antibody
  • MMP-9 Antibody
  • MMP9 Antibody
  • MMP9_HUMAN Antibody
  • Type V collagenase Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
    产品留言
    标题
    联系人
    联系电话
    内容
    验证码
    点击换一张
    注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
    2.如有必要,请您留下您的详细联系方式!

    沪公网安备 31011202007337号