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Anti-CD138 Antibody

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产品名称: Anti-CD138 Antibody
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简单介绍

Anti-CD138 Antibody


Anti-CD138 Antibody  的详细介绍
Name: Anti-CD138 Antibody
See all CD138 primary antibodies
Description: Mouse monoclonal (B-A38) antibody to CD138.
Specificity: The antibody B-A38 recognizes CD138 (syndecan 1), a 65-70 kDa heparan sulfate proteoglycan expressed mainly in the epidermis and plasma cells, but also in growth factor-stimulated lymphocytes.
Applications: FC, IHC
Reactivity: Human
Immunogen: U266 human peripheral blood myeloma cell line.
Host: Mouse
Clonality: Monoclonal
Clone: B-A38
Isotype: IgG1
Conjugate: Unconjugated
Purification: Protein A chromatography.
Concentration: 1 mg/ml
Purity: > 95% (by SDS-PAGE)
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.4, without Azide (0.2 μm filter sterilised).
Storage: Store at 2-8°C.
Function: Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413).
Sequence Similarities: Belongs to the syndecan proteoglycan family.
Post-Translational Modification: Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3.
Cellular Location: Membrane. Secreted. Secreted > Exosome.

Shedding of the ectodomain produces a soluble form.
Database Links:
  • Entrez Gene: 6382?Human
  • Omim: 186355?Human
  • SwissProt: P18827?Human
  • Unigene: 224607?Human
  • Unigene: 665958?Human
    		•
    Synonyms:
  • CD138 Antibody
  • CD138 antigen Antibody
  • CD_antigen Antibody
  • heparan sulfate proteoglycan fibroblast growth factor receptor Antibody
  • SDC Antibody
  • Sdc1 Antibody
  • SDC1_HUMAN Antibody
  • SYND1 Antibody
  • Syndecan Antibody
  • Syndecan 1 Antibody
  • syndecan proteoglycan 1 Antibody
  • Syndecan-1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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