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Anti-Vimentin Antibody

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产品名称: Anti-Vimentin Antibody
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简单介绍

Anti-Vimentin Antibody


Anti-Vimentin Antibody  的详细介绍
Name: Anti-Vimentin Antibody
See all Vimentin primary antibodies
Description: Mouse monoclonal (V9) antibody to Vimentin.
Applications: IHC
Reactivity: Human, Bovine, Canine, Hamster, Horse, Chicken, Monkey, Porcine, Rabbit
Immunogen: Purified Vimentin from porcine lense.
Host: Mouse
Clonality: Monoclonal
Clone: V9
Isotype: IgG1
Conjugate: Unconjugated
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.3, with 0.09% Sodium Azide.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.
Sequence Similarities: Belongs to the intermediate filament family.
Post-Translational Modification: One of the most prominent phosphoproteins in various cells of mesenchymal origin. Phosphorylation is enhanced during cell division, at which time vimentin filaments are significantly reorganized. Phosphorylation by PKN1 inhibits the formation of filaments. Filament disassembly during mitosis is promoted by phosphorylation at Ser-55 as well as by nestin. Phosphorylated at Ser-56 by CDK5 during neutrophil secretion in the cytoplasm. Phosphorylated by STK33 (By similarity).
Database Links:
  • Entrez Gene: 420519?Chicken
  • Entrez Gene: 280955?Cow
  • Entrez Gene: 477991?Dog
  • Entrez Gene: 101824289?Hamster
  • Entrez Gene: 7431?Human
  • Entrez Gene: 100522394?Pig
  • Omim: 193060?Human
  • SwissProt: P09654?Chicken
  • SwissProt: P48616?Cow
  • SwissProt: P02544?Hamster
  • SwissProt: P08670?Human
  • SwissProt: P02543?Pig
  • Unigene: 455493?Human
  • Unigene: 691131?Human
    		•
    Synonyms:
  • CTRCT30 Antibody
  • Epididymis luminal protein 113 Antibody
  • FLJ36605 Antibody
  • HEL113 Antibody
  • VIM Antibody
  • Vimentin Antibody
  • VIME_HUMAN Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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