产品资料

Anti-c-Myc Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-c-Myc Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-c-Myc Antibody


Anti-c-Myc Antibody  的详细介绍
Name: Anti-c-Myc Antibody
See all c-Myc primary antibodies
Description: Mouse monoclonal (9E10) antibody to c-Myc.
Specificity: The antibody 9E10 may be used to detect the c-Myc tag.
Applications: FC, IP, WB, IHC-P
Reactivity: Human
Immunogen: Synthetic peptide sequence (AEEQKLISEEDLL) corresponding to the C-terminal region of human c-Myc.
Host: Mouse
Clonality: Monoclonal
Clone: 9E10
Isotype: IgG1
Conjugate: Unconjugated
Purification: Protein A chromatography.
Concentration: 1 mg/ml
Purity: > 95% (by SDS-PAGE)
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.4, with 15mM Sodium Azide.
Storage: Store at 2-8°C.
Function: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.
Involvement in Disease: Burkitt lymphoma: A form of undifferentiated malignant lymphoma commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass.
Post-Translational Modification: Phosphorylated by PRKDC. Phosphorylation at Ser-329 by PIM2 leads to the stabilization of MYC (By similarity). Phosphorylation at Ser-62 by CDK2 prevents Ras-induced senescence. Phosphorylated at Ser-62 by DYRK2; this primes the protein for subsequent phosphorylation by GSK3B at Thr-58. Phosphorylation at Thr-58 and Ser-62 by GSK3 is required for ubiquitination and degradation by the proteasome.
Cellular Location: Nucleus > Nucleoplasm. Nucleus > Nucleolus.
Biotechnological Use: POU5F1/OCT4, SOX2, MYC/c-Myc and KLF4 are the four Yamanaka factors. When combined, these factors are sufficient to reprogram differentiated cells to an embryonic-like state designated iPS (induced pluripotent stem) cells. iPS cells exhibit the morphology and growth properties of ES cells and express ES cell marker genes.
Database Links:
  • Entrez Gene: 4609?Human
  • Omim: 190080?Human
  • SwissProt: P01106?Human
  • Unigene: 202453?Human
    		•
    Synonyms:
  • AU016757 Antibody
  • Avian myelocytomatosis viral oncogene homolog Antibody
  • bHLHe39 Antibody
  • c Myc Antibody
  • c-Myc Antibody
  • Class E basic helix-loop-helix protein 39 Antibody
  • MRTL Antibody
  • Myc Antibody
  • Myc Epitope Tag Antibody
  • Myc protein Antibody
  • Myc proto oncogene protein Antibody
  • Myc proto-oncogene protein Antibody
  • myc related translation/localization regulatory factor Antibody
  • myc-related translation/localization regulatory factor Antibody
  • Myc2 Antibody
  • MYCC Antibody
  • MYC_HUMAN Antibody
  • Myelocytomatosis oncogene Antibody
  • Niard Antibody
  • Nird Antibody
  • oncogene c-Myc Antibody
  • Oncogene Myc Antibody
  • OTTHUMP00000158589 Antibody
  • Proto-oncogene c-Myc Antibody
  • Protooncogene homologous to myelocytomatosis virus Antibody
  • RNCMYC Antibody
  • Transcription factor p64 Antibody
  • Transcriptional regulator Myc-A Antibody
  • v myc avian myelocytomatosis viral oncogene homolog Antibody
  • v myc myelocytomatosis viral oncogene homolog Antibody
  • V-Myc avian myelocytomatosis viral oncogene homolog Antibody
  • v-myc myelocytomatosis viral oncogene homolog (avian) Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
    产品留言
    标题
    联系人
    联系电话
    内容
    验证码
    点击换一张
    注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
    2.如有必要,请您留下您的详细联系方式!

    沪公网安备 31011202007337号