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Anti-MAP2 Antibody

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产品名称: Anti-MAP2 Antibody
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简单介绍

Anti-MAP2 Antibody


Anti-MAP2 Antibody  的详细介绍
Name: Anti-MAP2 Antibody
See all MAP2 primary antibodies
Description: Chicken polyclonal antibody to MAP2.
Applications: WB, IF/ICC, IHC
Dilutions: WB: 1:20,000. IF/ICC and IHC: 1:10,000-1:20,000.
Reactivity: Human, Horse, Cow, Porcine, Chicken, Rat, Mouse
Immunogen: Recombinant human projection domain sequence, amino acids 377-1505.
Host: Chicken
Clonality: Polyclonal
Isotype: IgY
Conjugate: Unconjugated
Concentration: 21.0 mg/ml
Purity: IgY preparation.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.
Storage: Store at 4°C.
Function: The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
Post-Translational Modification: Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly. Isoform 3/MAP2c is probably phosphorylated by PKA at Ser-319, Ser-350 and Ser-382 and by FYN at Tyr-67. The interaction with KNDC1 enhances MAP2 threonine phosphorylation (By similarity).
Cellular Location: Cytoplasm > Cytoskeleton. Cell projection > Dendrite.
Database Links:
  • Entrez Gene: 4133?Human
  • Entrez Gene: 17756?Mouse
  • Entrez Gene: 25595?Rat
  • Omim: 157130?Human
  • SwissProt: P11137?Human
  • SwissProt: P20357?Mouse
  • SwissProt: P15146?Rat
  • Unigene: 368281?Human
  • Unigene: 256966?Mouse
  • Unigene: 436793?Mouse
  • Unigene: 10484?Rat
  • Unigene: 136301?Rat
  • Unigene: 230443?Rat
    		•
    Synonyms:
  • DKFZp686I2148 Antibody
  • MAP 2 Antibody
  • MAP dendrite specific Antibody
  • MAP-2 Antibody
  • MAP2 Antibody
  • MAP2A Antibody
  • MAP2B Antibody
  • MAP2C Antibody
  • Microtubule associated protein 2 Antibody
  • Microtubule-associated protein 2 Antibody
  • MTAP2_HUMAN Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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