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PURE - anti mouse CD90 - Clone G7

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产品名称: PURE - anti mouse CD90 - Clone G7
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PURE - anti mouse CD90 - Clone G7


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PURE - anti Mouse CD90 - G7

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90,00 € tax excl.

265,00 € tax excl.

Product Description

  • G7
  • Rat IgG2c
  • Flow Cytometry
  • PURE
  • 0.5 mg/ml
  • Mouse T-cell hybridoma C 6/68
  • Mouse
  • The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
  • RUO
  • CD90, clone G7, is a mAb intended for RUO in the identification of cells that express CD90. This reagent is effective for direct IF staining of mouse sample for FCM analysis using ≤1 μg/106 cells.
  • Liquid
  • Store in the dark at 2-8 °C
Mouse PU-PP-B Vial View larger
CD90 reacts with the Thy-1.1 and Thy-1.2 alloantigens (CD90.1 and CD90.2, respectively) on thymocytes, peripheral T lymph ocytes, some intraepithelial T lymph ocytes (IEL, DEC), and neurons, but not B lymph ocytes, of all mouse strains. CD90 is a GPI-anchored membrane glycoprotein of the Ig superfamily which is involved in signal transduction. In addition, there is evidence that CD90 mediates adhesion of thymocytes to thymic stroma. Soluble G7 mAb stimulates murine T-cell proliferation and IL-2 secretion, via signalling through the TCR/CD3 complex. mAb G7 has been reported to promote apoptosis of thymocytes and CTL clones, as determined by morphological and biochemical criteria. The Thy-1-triggered thymocyte death was found to be developmentally regulated and targeted mainly within the CD4+CD8+CD3- and CD4+CD8+CD3lo cultured immature thymocytes. G7 antibody does not react with Thy-1 (CD90) on rat thymocytes.
  • Thy-1, Thy1
  • 25-35 kD
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