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This antibody reacts with the CD20-antigen, which has a bit wide including some dendritic cells, endothelial cells on vessels epithelial cells, some macrophages and some activated T cells. CD20 antigen is present on 8-16% of normal peripheral blood lymphocytes. CD20 MoAb recognizes type III unglycosylated phosphoprotein which crosses the cell membrane four times called TM4.
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