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Apoptosis is characterized by a variety of morphological features. One of the earliest indications of apoptosis is the translocation of the membrane phospholipid phosphatidylserine (PS) from the inner to the outer leaflet of the plasma membrane. Once exposed to the extracellular environment, s on PS become available for Annexin V, a 35-36 kDa, Ca 2+-dependent, phospholipid binding protein with a high affinity for PS. The translocation of PS precedes other apoptotic processes such as loss of plasma membrane integrity, DNA fragmentation, and chromatin condensation. As such, Annexin V can be conjugated to biotin or to a fluorochrome, and used for the easy, flow cytometric identification of cells in the early stages of apoptosis.
Aplication Reference:
Vagace JM et al. Etiopathological mechanisms and clinical characteristics of hyperhemolysis syndrome in Spanish patients with thalassemia. 2016 Annals of HematologyPerez-Peña, J et al. In silico analyses guides selection of BET inhibitors for triple negative breast cancer treatment. 2016 American Association for Cancer ResearchMoran J et al. Effects of Estrogen and Phytoestrogen Treatment on an In Vitro Model of Recurrent Stroke on HT22 Neuronal Cell Line. 2016 Cell Mol Neurobiol.Chamorro-Garcia, R. et al. AF10 Plays a Key Role in the Survival of Uncommitted Hematopoietic Cells. PLoS One. 2012; 7(12): e51626.Menacho-Márquez M. et al. The Rho Exchange Factors Vav2 and Vav3 Favor Skin Tumor Initiation and Promotion by Engaging Extracellular Signaling Loops. PLoS Biol. 2013 Jul; 11(7): e1001615
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