ABL (pY393/412) Antibody

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产品名称: ABL (pY393/412) Antibody

产品型号: abx011620

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ABL (pY393/412) Antibody

ABL (pY393/412) Antibody 的详细介绍

Phospho-ABL (Tyr393/412) Antibody detects endogenous levels of ABL only when phosphorylated at Tyrosine 393/412. The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-ABL protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene.

Target	ABL (pY393/412)
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Tested Applications	WB, IHC, IF/ICC
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	A synthesized peptide derived from human Abl around the phosphorylation site of Tyrosine 393/412.
Purification	Immunogen affinity purified.
Conjugation	Unconjugated
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight	135 kDa
Swiss Prot	P00519 P42684
Enzyme Commission Number	EC 2.7.10.2
Buffer	Rabbit IgG in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

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