ABL (pY204) Antibody

点击看大图

如果您对该产品感兴趣的话,可以

产品名称: ABL (pY204) Antibody

产品型号: abx032003

产品展商: 其它品牌

产品文档: 无相关文档

简单介绍

ABL (pY204) Antibody

ABL (pY204) Antibody 的详细介绍

ABL1 is a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-ABL protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t (9;22) translocation results in the head-to-tail fusion of the BCR and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1.

Target	ABL (pY204)
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Tested Applications	IF/ICC
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Human ABL (phospho-Tyr204).
Purification	Peptide Affinity Purified Rabbit Polyclonal Antibody.
Isotype	IgG
Conjugation	Unconjugated
Specificity	This ABL Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y204 of human ABL.
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Swiss Prot	P00519
Buffer	PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!