ABCG5 Antibody

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产品名称: ABCG5 Antibody

产品型号: abx015758

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简单介绍

ABCG5 Antibody

ABCG5 Antibody 的详细介绍

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins transport various molecules across extra- and intra-cellular membranes.ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).This protein is a member of the White subfamily.The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols.It is expressed in a tissue-specific manner in the liver, colon, and intestine.This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8.Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia.

Target	ABCG5
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Tested Applications	ELISA, WB, FCM
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Purified recombinant fragment of human ABCG5 (AA: 306-367) expressed in E. coli.
Purification	Purified antibody
Isotype	IgG₁
Conjugation	Unconjugated
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight	72.5 kDa
Concentration	1.0 mg/ml
Buffer	PBS with 0.05% sodium azide and 0.5% protein stabilizer.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

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