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27Kip1 Antibody

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产品名称: 27Kip1 Antibody
产品型号: abx032765
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简单介绍

27Kip1 Antibody


27Kip1 Antibody  的详细介绍
p27Kip1 is a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.

Target 27Kip1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Tested Applications IF/ICC
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Immunogen Human 27Kip1.
Purification Peptide Affinity Purified Rabbit Polyclonal Antibody.
Isotype IgG
Conjugation Unconjugated
Specificity This 27Kip1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-194 amino acids from the C-terminal region of human 27Kip1.
Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Swiss Prot P46527
Buffer PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
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