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Rabbit Anti Human PAI-1 Antiserum

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产品名称: Rabbit Anti Human PAI-1 Antiserum
产品型号: IASHPAI
产品展商: Innov-Research
产品文档: 无相关文档

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Rabbit Anti Human PAI-1 Antiserum


Rabbit Anti Human PAI-1 Antiserum  的详细介绍

Product Description

Rabbit Anti Human PAI-1 Antiserum


Rabbit Anti Human PAI-1 Antiserum is a polyclonal antiserum (host rabbit). Specifically recognizes human PAI-1 (Plasminogen Activator Inhibitor-1), otherwise known as SERPINE1, a 45kDa serine protease inhibitor and member of the serpin family, which acts as the primary inhibitor of tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA), and hence fibrinolysis.

Increased levels of PAI-1 are associated with diabetes, cardiovascular disease and an increased occurrence of thrombosis in obesity, and can be induced by obesity related factors including insulin, glucose and VLDL (Very-Low-Density Lipoprotein).

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