BioMag® anti-Human CD IgG-coated particles are produced by covalently attaching murine monoclonal antibodies to BioMag® particles. The antibodies were prepared against human leukocyte differentiation antigens. Each product is supplied in phosphate buffered saline with EDTA and sodium azide added as stabilizers, and should be washed in sterile media prior to use to remove the preservative.
CD34 antigen is expressed on hematopoietic progenitor cells of all lineages and on the most primitive pluripotent stem cells. CD34 expression is highest on the earliest stem cells and is gradually lost as the progenitor cells become committed and differentiate. CD34 antigen is also expressed on capillary endothelial cells and on bone marrow stromal cells.
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