BioMag® anti-Human CD IgG-coated particles are produced by covalently attaching murine monoclonal antibodies to BioMag® particles. The antibodies were prepared against human leukocyte differentiation antigens. Each product is supplied in phosphate buffered saline with EDTA and sodium azide added as stabilizers, and should be washed in sterile media prior to use to remove the preservative.
The CD19 antigen is expressed on all normal B lymphocytes and pro-B lymphocytes. CD19 expression is lost as the B lymphocytes progress to mature plasma cells. It is also found on the surface of follicular dentritic cells, early cells of the myelomonocytic lineage and on stabilized B cell lines. It is not present on T lymphocytes, NK cells, monocytes, and granulocytes.
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