BioMag® anti-Human CD IgG-coated particles are produced by covalently attaching murine monoclonal antibodies to BioMag® particles. The antibodies were prepared against human leukocyte differentiation antigens. Each product is supplied in phosphate buffered saline with EDTA and sodium azide added as stabilizers, and should be washed in sterile media prior to use to remove the preservative.
The CD8 molecule is found on a T cell subset of human peripheral blood lymphocytes, the suppressor/cytotoxic T lymphocytes. Certain NK cells may also express the CD8 antigen, but with low to medium density of expression. CD8 is also present on most thymocytes where it is frequently co-expressed with CD4, and on a subpopulation of bone marrow cells.
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